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Fever with thrombocytopenia associated with a novel bunyavirus in China.
BACKGROUND Heightened surveillance of acute febrile illness in China since 2009 has led to the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown cause. Infection… Expand
Association of low serum 25-hydroxyvitamin D levels and mortality in the critically ill*
Objective:We hypothesized that deficiency in 25-hydroxyvitamin D before hospital admission would be associated with all-cause mortality in the critically ill. Design:Multicenter observational study… Expand
Absorption and metabolism of flavonoids in the caco-2 cell culture model and a perused rat intestinal model.
The purpose of present study was to determine the intestinal absorption and metabolism of genistein and its analogs to better understand the mechanisms responsible for their low oral bioavailability.… Expand
MicroRNA-638 is highly expressed in human vascular smooth muscle cells and inhibits PDGF-BB-induced cell proliferation and migration through targeting orphan nuclear receptor NOR1.
AIMS Aberrant vascular smooth muscle cell (VSMC) proliferation and migration contribute significantly to the development of vascular pathologies, such as atherosclerosis and restenosis. MicroRNAs… Expand
Heterosynaptic Scaling of Developing GABAergic Synapses: Dependence on Glutamatergic Input and Developmental Stage
A proportionality or balance between coactivated excitatory and inhibitory inputs is often observed for individual cortical neurons and is proposed to be important for their functions. This feature… Expand
Differentiation of human bone marrow mesenchymal stem cells into bladder cells: potential for urological tissue engineering.
- H. Tian, S. Bharadwaj, Y. Liu, P. Ma, A. Atala, Y. Zhang
- Biology, Medicine
- Tissue engineering. Part A
- 4 March 2010
Bone marrow mesenchymal stem cells (BMSCs) are capable of differentiating into multiple cell types, providing an alternative cell source for cell-based therapy and tissue engineering. Simultaneous… Expand
Differences between top-down and bottom-up approaches in mineralizing thick, partially demineralized collagen scaffolds.
Biominerals exhibit complex hierarchical structures derived from bottom-up self-assembly mechanisms. Type I collagen serves as the building block for mineralized tissues such as bone and dentin. In… Expand
The use of sodium trimetaphosphate as a biomimetic analog of matrix phosphoproteins for remineralization of artificial caries-like dentin.
- Y. Liu, N. Li, +6 authors F. Tay
- Medicine, Materials Science
- Dental materials : official publication of the…
- 1 May 2011
OBJECTIVES This study examined the use of sodium trimetaphosphate (STMP) as a biomimetic analog of matrix phosphoproteins for remineralization of artificial carious-affected dentin. METHODS… Expand
A Structure-Guided Mutation in the Major Capsid Protein Retargets BK Polyomavirus
Viruses within a family often vary in their cellular tropism and pathogenicity. In many cases, these variations are due to viruses switching their specificity from one cell surface receptor to… Expand
Human urine-derived stem cells seeded in a modified 3D porous small intestinal submucosa scaffold for urethral tissue engineering.
- Shaofeng Wu, Y. Liu, S. Bharadwaj, A. Atala, Y. Zhang
- Medicine, Materials Science
- 1 February 2011
The goal of this study was to determine whether urothelial cells (UC) and smooth muscle cells (SMC) derived from the differentiation of urine-derived stem cells (USC) could be used to form engineered… Expand