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Structural and functional multiplicity of the kisspeptin/GPR54 system in goldfish (Carassius auratus).
To ascertain the neuroendocrine function of the kisspeptin/GPR54 system in non-mammalian species, full-length cDNAs encoding for Kiss1 and Kiss2 as well as their putative cognate receptors GPR54a and… Expand
Whole-exome and targeted gene sequencing of gallbladder carcinoma identifies recurrent mutations in the ErbB pathway
Individuals with gallbladder carcinoma (GBC), the most aggressive malignancy of the biliary tract, have a poor prognosis. Here we report the identification of somatic mutations for GBC in 57… Expand
Characterization of the Palmitoylation Domain of SNAP‐25
Abstract: SNAP‐25 (synaptosomal associated protein of 25 kDa) is a neural specific protein that has been implicated in the synaptic vesicle docking and fusion process. It is tightly associated with… Expand
Genomic analysis of oesophageal squamous-cell carcinoma identifies alcohol drinking-related mutation signature and genomic alterations
Approximately half of the world's 500,000 new oesophageal squamous-cell carcinoma (ESCC) cases each year occur in China. Here, we show whole-genome sequencing of DNA and RNA in 94 Chinese individuals… Expand
Genetic Polymorphisms in Pre-microRNAs and Risk of Ischemic Stroke in a Chinese Population
- Y. Liu, Y. Ma, B. Zhang, Shun-Xian Wang, X. Wang, Ju-ming Yu
- Journal of Molecular Neuroscience
- 1 April 2014
Ischemic stroke is considered to be a complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors. MicroRNAs participated in various… Expand
Insights into the Mechanisms Involved in the Expression and Regulation of Extracellular Matrix Proteins in Diabetic Nephropathy.
Diabetic Nephropathy (DN) is believed to be a major microvascular complication of diabetes. The hallmark of DN includes deposition of Extracellular Matrix (ECM) proteins, such as, collagen, laminin… Expand
Prenatal Fluoride Exposure and Cognitive Outcomes in Children at 4 and 6–12 Years of Age in Mexico
- M. Bashash, D. Thomas, +12 authors M. Hernández-Ávila
- Environmental health perspectives
- 1 September 2017
Background: Some evidence suggests that fluoride may be neurotoxic to children. Few of the epidemiologic studies have been longitudinal, had individual measures of fluoride exposure, addressed the… Expand
Hydrogen-Rich Saline Protects Myocardium Against Ischemia/Reperfusion Injury in Rats
Protective effect of hydrogen (H2) gas on cardiac ischemia-reperfusion (I/R) injury has been demonstrated previously. This study was designed to test the hypothesis that hydrogen-rich saline (saline… Expand
The development of a tissue-engineered artery using decellularized scaffold and autologous ovine mesenchymal stem cells.
Alternatives to using native arteries in vascular surgery are urgently needed. Vessels made from synthetic polymers have shortcomings such as thrombosis, rejection, intimal hyperplasia,… Expand
Molecular cloning and functional characterization of the first non-mammalian 26RFa/QRFP orthologue in Goldfish, Carassius auratus
- Y. Liu, Y. Zhang, S. Li, W. Huang, H. Lin
- Biology, Medicine
- Molecular and Cellular Endocrinology
- 6 May 2009
In this study, we used data mining approach to predict 26RFa/QRFP precursors from fish, amphibian, reptile and avian species and subsequently cloned a 26RFa/QRFP precursor cDNA from goldfish brain… Expand