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Transcriptional Adaptation of Mycobacterium tuberculosis within Macrophages
Little is known about the biochemical environment in phagosomes harboring an infectious agent. To assess the state of this organelle we captured the transcriptional responses of MycobacteriumExpand
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Empathy in Chinese medical students: psychometric characteristics and differences by gender and year of medical education
BackgroundIn recent years in China, the tense physician-patient relationship has been an outstanding problem. Empathy is one of the fundamental factors enhancing the therapeutic effects ofExpand
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Monitoring retinal morphologic and functional changes in mice following optic nerve crush.
PURPOSE We characterized the morphologic and functional changes in optic nerve crushed mice and evaluated electroretinogram (ERG) responses as tools to monitor retinal ganglion cell (RGC)Expand
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Pre-treatment neutrophil-to-lymphocyte ratio is associated with neutrophil and T-cell infiltration and predicts clinical outcome in patients with glioblastoma
BackgroundMarkers of systemic inflammation are correlated with patient survival in various cancers. The prognostic value of neutrophil-to-lymphocyte ratio (NLR) was compared with that ofExpand
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No detectable resistance to tenofovir disoproxil fumarate after 6 years of therapy in patients with chronic hepatitis B
One major challenge in the treatment of chronic hepatitis B is to maintain long‐term viral suppression without promoting the selection of drug‐resistant mutations. We analyzed data from 347 hepatitisExpand
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Receptor for advanced glycation end products and age-related macular degeneration.
  • K. Howes, Y. Liu, +4 authors W. Baehr
  • Biology, Medicine
  • Investigative ophthalmology & visual science
  • 1 October 2004
PURPOSE Advanced glycation end products (AGE) exacerbate disease progression through two general mechanisms: modifying molecules and forming nondegradable aggregates, thus impairing normalExpand
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Ionizing radiation stimulates secretion of pro-inflammatory cytokines: dose–response relationship, mechanisms and implications
In previous studies we showed a marked increase in secretion of inflammatory cytokines TNFα and interleukin (IL)-1β by mouse macrophages in response to different doses of ionizing radiation (IR).Expand
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Overexpression of collagenase (MMP-1) and stromelysin (MMP-3) by pterygium head fibroblasts.
BACKGROUND The balance between matrix metalloproteinases (MMPs) and the tissue inhibitors of metalloproteinases (TIMPs) determines the extent of connective tissue degradation and remodeling. Expand
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Satiety dysfunction in Prader-Willi syndrome demonstrated by fMRI
The neurobiology relating to the insatiable appetite observed in Prader-Willi syndrome (PWS) has not been fully characterised. Two functional magnetic resonance imaging (fMRI) scans were performed onExpand
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Recent advances of sonodynamic therapy in cancer treatment
Sonodynamic therapy (SDT) is an emerging approach that involves a combination of low-intensity ultrasound and specialized chemical agents known as sonosensitizers. Ultrasound can penetrate deeplyExpand
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