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Curcumin down-regulates the multidrug-resistance mdr1b gene by inhibiting the PI3K/Akt/NF kappa B pathway.
Flavonoid 3'-O-methyltransferase from rice: cDNA cloning, characterization and functional expression.
Antioxidative activity of persimmon and grape seed extract: in vitro and in vivo
Characterization of Flavonoid 7-O-Glucosyltransferase from Arabidopsis thaliana
- J. H. Kim, B. Kim, Joong-Hoon Ahn
- Biology, MedicineBioscience, biotechnology, and biochemistry
- 23 June 2006
Results indicate that AtGT-2 encodes a flavonoid 7-O-glucosyltransferase, which transfers a glucose molecule into several different kinds of flavonoids, eriodictyol being the most effective substrate, followed by luteolin, kaempferol, and quercetin.
Molecular cloning, expression and characterization of a glycosyltransferase from rice
This is the first time that the function of a rice UGT has been characterized, and the most efficient substrate was kaempferol, followed by apigenin, genistein and luteolin, in that order.
Characterization of flavone synthase I from rice.
OsFNS I-1 encodes a flavone synthase I, the first type I FNS I found outside of the Apiaceae family, and it is found that the cofactors oxoglutarate, FeSO(4), ascorbate and catalase are required for this reaction.
Deoxypodophyllotoxin induces G2/M cell cycle arrest and apoptosis in HeLa cells.
The tricyclic antidepressant imipramine induces autophagic cell death in U-87MG glioma cells.
Cation dependent O-methyltransferases from rice
Two lower molecular mass OMT genes (ROMT-15 and -17) were cloned from rice and expressed in Escherichia coli as glutathione S-transferase fusion proteins, indicating that the metal ion has a critical role in the enzymatic methylation.
p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression.
Results indicate that ERK and JNK MAPK/Elk-1/Egr-1 signal cascade is required for p53-independent transcriptional activation of p21(Waf1/Cip1) in response to curcumin in U-87MG human glioblastoma cells.