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Acute toxicity and pharmacokinetics of 13 nm-sized PEG-coated gold nanoparticles.
In general, gold nanoparticles are recognized as being as nontoxic. Still, there have been some reports on their toxicity, which has been shown to depend on the physical dimension, surface chemistry,Expand
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Selection of Quantum Dot Wavelengths for Biomedical Assays and Imaging
Fluorescent semiconductor nanocrystals (quantum dots [QDs]) are hypothesized to be excellent contrast agents for biomedical assays and imaging. A unique property of QDs is that their absorbanceExpand
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Pathobiological features of a novel, highly pathogenic avian influenza A(H5N8) virus
The endemicity of highly pathogenic avian influenza (HPAI) A(H5N1) viruses in Asia has led to the generation of reassortant H5 strains with novel gene constellations. A newly emerged HPAI A(H5N8)Expand
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Phase morphology and rheological behavior of polymer/layered silicate nanocomposites
Abstract Rheological behavior of polymer/layered silicate nanocomposites are strongly dependent not only upon their microstructure but also upon the interfacial characteristics. Different phaseExpand
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Noninvasive imaging of dendritic cell migration into lymph nodes using near‐infrared fluorescent semiconductor nanocrystals
Effective tracking of immunotherapeutic cells is essential for monitoring the migration of injected cells to the target tissue. Here we report the use of near‐infrared (NIR) ‐emitting fluorescentExpand
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Indocyanine green as a near-infrared fluorescent agent for identifying parathyroid glands during thyroid surgery in dogs
BackgroundSurgical procedures involving the thyroid gland require identification of the parathyroid glands. Indocyanine green (ICG) is a near-infrared (NIR) fluorescent contrast agent used for aExpand
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Multivalent Polymer Nanocomplex Targeting Endosomal Receptor of Immune Cells for Enhanced Antitumor and Systemic Memory Response.
We have designed and synthesized linear polymer-based nanoconjugates and nanocomplexes bearing multivalent immunostimulatory ligands and also demonstrated that the synthetic multivalent nanocomplexesExpand
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Quantum dot‐based protein micro‐ and nanoarrays for detection of prostate cancer biomarkers
In this article, we demonstrate the fabrication and detection of cancer protein biochips consisting of micro‐ and nanoarrays whereby pegylated quantum dots (QDs) conjugated to antibodies (Abs) ofExpand
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Polymer nanoparticles for enhanced immune response: combined delivery of tumor antigen and small interference RNA for immunosuppressive gene to dendritic cells.
In this study, we report on polymer nanoparticles (NPs) that can induce an enhanced immune response in dendritic cell (DC)-based cancer immunotherapy by the combined delivery of tumor antigen andExpand
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Perfluorodecalin/[InGaP/ZnS quantum dots] nanoemulsions as 19F MR/optical imaging nanoprobes for the labeling of phagocytic and nonphagocytic immune cells.
Multimodal imaging contrast agents with unique magnetic resonance (MR) and optical imaging capabilities have great potentials in the diagnosis and therapy of disease. Using a rational materialsExpand
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