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The genome of Aiptasia, a sea anemone model for coral symbiosis
- S. Baumgarten, O. Simakov, C. Voolstra
- Biology, Environmental ScienceProceedings of the National Academy of Sciences
- 31 August 2015
The assembly and analysis of the Aiptasia genome is reported on, which will provide a foundation for future studies and has revealed several features that may be key to understanding the evolution and function of the endosymbiosis.
Genomes of coral dinoflagellate symbionts highlight evolutionary adaptations conducive to a symbiotic lifestyle
Comparative analyses of genome and transcriptome protein sets show that all dinoflagellates, not only Symbiodinium, possess significantly more transmembrane transporters involved in the exchange of amino acids, lipids, and glycerol than other eukaryotes.
Integrating microRNA and mRNA expression profiling in Symbiodinium microadriaticum, a dinoflagellate symbiont of reef-building corals
Identification and characterization of Symbiodinium's smRNA repertoire establishes the possibility of a range of gene regulatory mechanisms in dinoflagellates acting post-transcriptionally, and identified a variety of processes that could be under microRNA control.
DNA methylation regulates transcriptional homeostasis of algal endosymbiosis in the coral model Aiptasia
It is demonstrated that DNA methylation provides an epigenetic mechanism of transcriptional homeostasis that responds to symbiosis and shows enrichment for symbiosis-related processes, such as immunity, apoptosis, phagocytosis recognition, and phagosome formation, and reveal intricate interactions between the underlying pathways.
Comparative genomics explains the evolutionary success of reef-forming corals
Transcriptome and genome data from twenty stony coral species and a selection of reference bilaterians were studied to elucidate coral evolutionary history. We identified genes that encode the…
DNA Methylation Cancer Biomarkers: Translation to the Clinic
Existing DNA methylation cancer biomarkers used in clinical practice are summarized, technical factors such as the analytical performance and product-market fit, factors that contribute to successful downstream investment, including geography, and how this impacts intellectual property, regulatory hurdles, and the future of the marketplace and healthcare system are discussed.
Long-Term Temperature Stress in the Coral Model Aiptasia Supports the “Anna Karenina Principle” for Bacterial Microbiomes
- Hanin Ibrahim Ahmed, M. Herrera, Y. Liew, M. Aranda
- Biology, Environmental ScienceFront. Microbiol.
- 8 May 2019
Investigating the bacterial communities of different Aiptasia host-symbiont combinations under long-term heat stress in laboratory conditions found a higher number of taxa, and consequently increased α-diversity and β-dispersion, were observed in the microbiomes of heat-stressed individuals across all host strains and experimental batches.
Identification of MicroRNAs in the Coral Stylophora pistillata
First evidence of a functional RNAi machinery and five conserved miRNAs in S. pistillata is presented, implying that miRNAAs play a role in organismal biology of scleractinian corals and potential roles in symbiosis and coral calcification are suggested.
Epigenome-associated phenotypic acclimatization to ocean acidification in a reef-building coral
Analysis of DNA methylation patterns of corals subjected to long-term pH stress showed widespread changes in pathways regulating cell cycle and body size, which suggest an epigenetic component in phenotypic acclimatization that provides corals with an additional mechanism to cope with environmental change.
Intergenerational epigenetic inheritance in reef-building corals
Examination of intergenerational DNA methylation profiles in a reef-building coral shows there to be genome-wide inheritance, with the potential for adaptive capacity to environmental stressors, which could extend to enhancing their capacity to adapt to climate change.