• Publications
  • Influence
T0070907, a Selective Ligand for Peroxisome Proliferator-activated Receptor γ, Functions as an Antagonist of Biochemical and Cellular Activities*
The nuclear hormone receptor peroxisome proliferator-activated receptor γ (PPARγ (NR1C3)) plays a central role in adipogenesis and is the molecular target for the thiazolidinedione (TZD) class ofExpand
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The triggering of apoptosis in macrophages by pristine graphene through the MAPK and TGF-beta signaling pathways.
With the development of nanotechnology and the wide use of graphene, it has become necessary to assess the potential biological adverse effects of graphene. However, most of the recent publicationsExpand
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Novel Peroxisome Proliferator-activated Receptor (PPAR) γ and PPARδ Ligands Produce Distinct Biological Effects*
The peroxisome proliferator-activated receptors (PPARs) include three receptor subtypes encoded by separate genes: PPARα, PPARδ, and PPARγ. PPARγ has been implicated as a mediator of adipocyteExpand
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The c-Src Tyrosine Kinase Regulates Signaling of the Human DF3/MUC1 Carcinoma-associated Antigen with GSK3β and β-Catenin*
The DF3/MUC1 mucin-like glycoprotein is aberrantly overexpressed in most human carcinomas. The cytoplasmic domain of MUC1 interacts with glycogen synthase kinase 3β (GSK3β) and thereby decreasesExpand
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Organization of the connections between claustrum and cortex in the mouse
The connections between the claustrum and the cortex in mouse are systematically investigated with adeno‐associated virus (AAV), an anterograde viral tracer. We first define the boundary and theExpand
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FGF19-induced Hepatocyte Proliferation Is Mediated through FGFR4 Activation
  • X. Wu, H. Ge, +8 authors Y. Li
  • Biology, Medicine
  • The Journal of Biological Chemistry
  • 15 December 2009
FGF19 and FGF21, unique members of the fibroblast growth factor (FGF) family, are hormones that regulate glucose, lipid, and energy homeostasis. Increased hepatocyte proliferation and liver tumorExpand
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The first synthetic agonists of FFA2: Discovery and SAR of phenylacetamides as allosteric modulators.
Free fatty acid receptor 2 (FFA2) is a G-protein coupled receptor for which only short-chain fatty acids (SCFAs) have been reported as endogenous ligands. We describe the discovery and optimizationExpand
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The Putative Tumor Suppressor LRP1B, a Novel Member of the Low Density Lipoprotein (LDL) Receptor Family, Exhibits Both Overlapping and Distinct Properties with the LDL Receptor-related Protein*
The low density lipoprotein receptor-related protein-deleted in tumor (LRP1B, initially referred to as LRP-DIT) was cloned and characterized as a candidate tumor suppressor. It is a new member of theExpand
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The Role of SDF-1-CXCR4/CXCR7 Axis in the Therapeutic Effects of Hypoxia-Preconditioned Mesenchymal Stem Cells for Renal Ischemia/Reperfusion Injury
In vitro hypoxic preconditioning (HP) of mesenchymal stem cells (MSCs) could ameliorate their viability and tissue repair capabilities after transplantation into the injured tissue through yetExpand
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Endocytic receptor LRP together with tPA and PAI‐1 coordinates Mac‐1‐dependent macrophage migration
Migration of activated macrophages is essential for resolution of acute inflammation and the initiation of adaptive immunity. Here, we show that efficient macrophage migration in inflammatoryExpand
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