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Fullerene derivatives protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused lungs.
Results indicate that polyhydroxylated fullerene derivatives C(60)(OH)(7+/-2) at low concentrations protect against oxidative stress in RAW 264.7 cells and ischemia-reperfused (IR) lungs. Expand
Overexpression of placenta growth factor contributes to the pathogenesis of pulmonary emphysema.
  • P. Tsao, Yi Su, +10 authors S. Hsu
  • Medicine
  • American journal of respiratory and critical care…
  • 15 February 2004
A persistently elevated PlGF was detrimental to the developed lung and causes the emphysematous change seen in the authors' TG mice, suggesting that PlGF plays an important role in the pathogenesis of pulmonaryEmphysema via its action on type II pneumocytes. Expand
Respiratory mechanics and maximal expiratory flow in the anesthetized mouse.
It is concluded that respiratory mechanical parameters of mice (after normalization with body weight) are similar to those of guinea pigs and rats and that forced expiratory maneuver is a useful technique to detect airway constriction in this species. Expand
Learning and memory in the mosquito Aedes aegypti shown by conditioning against oviposition deterrence
The female mosquitoes reared in repellent‐treated water were conditioned against oviposition site deterrence, as shown when choice tests were conducted 6 days post‐emergence from the treated water, demonstrating learning and memory in the mosquito Ae. Expand
Ventilation during prolonged hypercapnia in the rat.
Awake rats, with chronically implanted arterial catheters and abdominal thermistors, were continuously exposed to 5 or 7% CO2 in air in an environmental chamber for up to 3 wk, revealing extensive metabolic compensation for respiratory acidosis within 3-7 days. Expand
Immunoprophylaxis of allergen–induced immunoglobulin E synthesis and airway hyperresponsiveness in vivo by genetic immunization
The findings suggest that allergen–gene immunization is effective in modulating allergic responses, and may provide a novel therapeutic approach for allergic diseases. Expand
Ventilatory responses to acute CO2 exposure in the rat.
Oxygen radicals in bronchoconstriction of guinea pigs elicited by isocapnic hyperpnea.
  • Z. Fang, Y. Lai
  • Chemistry, Medicine
  • Journal of applied physiology
  • 1 February 1993
The role of oxygen radicals in isocapnic hyperpnea-induced bronchoconstriction of guinea pigs was investigated using scavengers of the radicals to test the effects of intratracheal administration of superoxide dismutase and catalase and tachykinin depletion. Expand
Lung Uptake of Tc‐99m HMPAO in Cigarette Smokers Expressed by Lung/Liver Activity Ratio
Lung/liver ratio uptake of Tc-99m HMPAO may be used as an indicator of cigarette smoking. Expand
End-expiratory and tidal volumes measured in conscious mice using single projection x-ray images.
In anesthetized BALB/c mice, conscious mice adapted to Mch by limiting R(aw), while anesthesia resulted in airway closure followed by diaphragm fatigue and failure. Expand