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Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain
No may play an important role in performance during the acquisition, but not retention, of the radial arm maze task, and endogenous NO may be involved in the regulation of monoamine metabolism.
Role of nitric oxide and cyclic GMP in the dizocilpine-induced impairment of spontaneous alternation behavior in mice
Vascular endothelial growth factor VEGF-like heparin-binding protein from the venom of Vipera aspis aspis (Aspic viper).
- Y. Komori, T. Nikai, K. Taniguchi, K. Masuda, H. Sugihara
- Biology, ChemistryBiochemistry
- 7 September 1999
The heparin-binding dimeric hypotensive factor (HF) was purified from Vipera aspis as pis (Aspic viper) venom and revealed that it exerted a strong hypotensive effect after intravenous injection of samples into a rat and is similar to that of VEGF.
The role of nitric oxide in dizocilpine-induced impairment of spontaneous alternation behavior in mice.
- K. Yamada, Y. Noda, T. Nabeshima
- Psychology, BiologyThe Journal of pharmacology and experimental…
- 1 February 1996
The results suggest that, although N-methyl-D-aspartate receptors play a critical role in both spatial working memory and long-term memory processes assessed by spontaneous alternation behavior and the passive avoidance, respectively, different neuronal mechanisms may be involved in these two processes.
Reduction in the number of NADPH-diaphorase-positive cells in the cerebral cortex and striatum in aged rats
Hemorrhagic activity and muscle damaging effect of Pseudomonas aeruginosa metalloproteinase (elastase).
The role of thiols in the apparent activation of rat brain nitric oxide synthase (NOS).
Thiol addition to a thiol-deplete preparation of the enzyme resulted in a 4 to 7-fold increase in activity when measured after 15 min, which is consistent with a cofactor role for thiols.
Biological properties of elastase inhibitor, AFLEI from Aspergillus flavus.
- Y. Okumura, K. Ogawa, K. Uchiya, Y. Komori, T. Nonogaki, T. Nikai
- BiologyNihon Ishinkin Gakkai zasshi = Japanese journal…
For the treatment of aspergillosis, combination of an existing antifungal agent with AFLEI can be expected to provide greater therapeutic benefits than administration of an antifundal agent alone.
Inhibition of purified nitric oxide synthase from rat cerebellum and macrophage by L-arginine analogs.
- Y. Komori, G. Wallace, J. Fukuto
- Biology, ChemistryArchives of biochemistry and biophysics
- 1 December 1994
NG-Methoxy-L-arginine appears to be an alternate substrate for NOS, whereas most other L- arginine analogs, except for the biosynthetic intermediate NG-hydroxy- L-argInine, do not elicit significant enzyme turnover.