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  • Influence
Gingipains in the culture supernatant of Porphyromonas gingivalis cleave CD4 and CD8 on human T cells.
Porphyromonas gingivalis has been shown to attack host defense systems through proteolytic cleavage of a wide variety of members of the systems. In this study, we examined the ability of P.Expand
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Coffee drinking and colorectal cancer and its subsites: A pooled analysis of 8 cohort studies in Japan
Coffee is a rich source of bioactive compounds that have potential anticarcinogenic effects. However, it remains unclear whether coffee drinking is associated with colorectal cancer. Also, despiteExpand
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Cigarette smoking, alcohol drinking, and oral cavity and pharyngeal cancer in the Japanese: a population-based cohort study in Japan
The effects of cigarette smoking and alcohol drinking on the incidence of oral cavity and pharyngeal cancer (OCPC) in the Asian population have been poorly understood. To assess the effects ofExpand
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Relationship of alcohol use, physical activity and dietary habits with serum carotenoids, retinol and alpha-tocopherol among male Japanese smokers.
BACKGROUND Despite considerable interest in the anticarcinogenic and anti-atherosclerotic effects of carotenoids and alpha-tocopherol, little is known about determinants of these serumExpand
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  • Open Access
Changes in regional cerebral blood volume in frontal cortex during mental work with and without caffeine intake: functional monitoring using near-infrared spectroscopy.
Near-infrared spectroscopy (NIRS) was used to measure frontal regional cerebral blood volume (rCBV) in a person whose brain was under the influence of pharmacological agents while the person wasExpand
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  • Open Access
Rationale, design, and profile of the Three-Prefecture Cohort in Japan: A 15-year follow-up
Background We reutilized the existing Three-Prefecture Cohort to evaluate the relationship between lifestyle factors and the incidence or mortality from non-communicable diseases. Methods This studyExpand
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Transcranial ultrasonography system for visualizing skull and brain surface aided by fuzzy expert system
A conventional ultrasonography system can noninvasively provide human tissue and blood flow velocity information with real-time processing. In general, since the human skull prevents the disclosureExpand
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Body-Mass Index and Pancreatic Cancer Incidence: A Pooled Analysis of Nine Population-Based Cohort Studies With More Than 340,000 Japanese Subjects
Background A high body mass index (BMI) has been proposed as an important risk factor for pancreatic cancer. However, this association of BMI with pancreatic cancer risk has not been confirmed inExpand
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  • Open Access
Trans-skull imaging system by ultrasonic array probe
In this paper, we propose a trans-skull imaging system of the human brain using an ultrasonic array probe. In it, we employ a cow scapula imitated to human skull and a steel with ditches imitated toExpand
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  • Open Access
Data synthesis for trans-skull brain imaging by 0.5 and 1.0MHz ultrasonic array systems
This paper describes a data synthesis method of two ultrasonic waves for visualizing brain image under skull. In it, we employ 0.5MHz and 1.0MHz ultrasonic array probes. We synthesize the waves ofExpand
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