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Biosynthesis of the amaryllidaceae alkaloid Galanthamine
- J. Eichhorn, T. Takada, Y. Kita, M. Zenk
- Chemistry, Biology
- 1 October 1998
Abstract Application of radioactively as well as 13C-labelled 4′-O-methylnorbelladine to organs of field grown Leucojum aestivum plants resulted in an optimal incorporation into galanthamine (27%),… Expand
Hypervalent iodine oxidation of p-alkoxyphenols and related compounds : a general route to p-benzoquinone monoacetals and spiro lactones
Oxydation de dimethoxy-, trimethoxy-, carboxy-2', ethyl, carboxy-2' ethoxy- et hydroxy-2' ethylphenols a l'aide du bis-trifluoroacetoxyiodo benzene
Versatile hypervalent-iodine(III)-catalyzed oxidations with m-chloroperbenzoic acid as a cooxidant.
- T. Dohi, A. Maruyama, Misaki Yoshimura, K. Morimoto, H. Tohma, Y. Kita
- Chemistry, Medicine
- Angewandte Chemie
- 26 September 2005
Hypervalent Iodine Reagents for the Oxidation of Alcohols and Their Application to Complex Molecule Synthesis
Hypervalent iodine(V) derivatives such as 2-iodoxybenzoic acid (IBX) and Dess–Martin periodinane [DMP; 1,1,1-tris(acetyloxy)-1,1-dihydro-1,2-benziodoxol-3-(1H)-one] have been used widely for the… Expand
Oxidative Intramolecular Phenolic Coupling Reaction Induced by a Hypervalent Iodine(III) Reagent: Leading to Galanthamine-Type Amaryllidaceae Alkaloids
- Y. Kita, M. Arisawa, +4 authors T. Takada
- Chemistry
- 22 August 1998
By extending our oxidative phenol-coupling reactions using a hypervalent iodine(III) reagent, a versatile synthetic procedure for the galanthamine-type Amaryllidaceae alkaloids was accomplished. The… Expand
An Oxidative Intramolecular Phenolic Coupling Reaction for the Synthesis of Amaryllidaceae Alkaloids Using a Hypervalent Iodine(III) Reagent
The oxidative intramolecular phenolic coupling reaction of norbelladine derivatives (1) was investigated with the aim of preparing amaryllidaceae alkaloids. Spirodienone compounds (2), which are… Expand
A Novel Efficient Synthesis of 1-Ethoxyvinyl Esters and Their Use in Acylation of Amines and Alcohols: Synthesis of Water-Soluble Oxaunomycin Derivatives
- Y. Kita, H. Maeda, Kana Omori, T. Okuno, Y. Tamura
- Chemistry
- 1993
The synthetic and biological studies of discorhabdins and related compounds.
- Y. Wada, Yu Harayama, +6 authors Y. Kita
- Chemistry, Medicine
- Organic & biomolecular chemistry
- 15 June 2011
Various analogues of the marine alkaloids, discorhabdins, have been synthesized. The strategy contains spirocyclization with phenyliodine(III) bis(trifluoroacetate) (PIFA), oxidative fragmentation of… Expand
A novel and efficient oxidative biaryl coupling reaction of phenol ether derivatives using a combination of hypervalent iodine(III) reagent and heteropoly acid.
- H. Hamamoto, G. Anilkumar, H. Tohma, Y. Kita
- Chemistry, Medicine
- Chemical communications
- 27 February 2002
A novel and efficient oxidative biaryl coupling reaction of phenol ether derivatives using a combination of hypervalent iodine(III) reagent, phenyliodine(III) bis(trifluoroacetate) (PIFA), and… Expand
Synthesis of the Marine Pyrroloiminoquinone Alkaloids, Discorhabdins
- Y. Wada, H. Fujioka, Y. Kita
- Biology, Medicine
- Marine drugs
- 21 April 2010
Many natural products with biologically interesting structures have been isolated from marine animals and plants such as sponges, corals, worms, etc. Some of them are discorhabdin alkaloids. The… Expand
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