• Publications
  • Influence
Secretory immunoglobulin a from human milk catalyzes milk protein phosphorylation
TLDR
Evidence that protein kinase activity is an intrin sic property of secretory immunoglobulin A from milk of healthy human mothers is presented and the likelihood that catalytic Abs are generated by the immune system of healthy mothers is suggested. Expand
Human breast milk immunoglobulins G hydrolyze nucleotides.
TLDR
It is shown for the first time that IgG from human milk (and their Fab-fragments) also catalyze hydrolysis of nucleoside mono-, di-, and triphosphates and that Igg can hydrolyze DNA and RNA. Expand
Phosphorylation of different human milk proteins by human catalytic secretory immunoglobulin A
The ability of secretory immunoglobulin A (sIgA) from milk of healthy mothers to phosphorylate various milk proteins in the presence of γ‐[32P]‐ATP was shown to be a property of the antibodies. TheExpand
Desialylation of dying cells with catalytically active antibodies possessing sialidase activity facilitate their clearance by human macrophages
TLDR
It is concluded that sialidase abzyme can serve as a protective agent in autoimmune patients and that artificial abzymes may be of potential therapeutic value. Expand
Anti‐histone H1 IgGs from blood serum of systemic lupus erythematosus patients are capable of hydrolyzing histone H1 and myelin basic protein
TLDR
Novel hydrolytic activity of the anti‐histone H1 antibodies (Ab) toward hist one H1 and myelin basic protein (MBP) was shown and intrinsic activity was confirmed to be an intrinsic property of the IgG molecule. Expand
Phosphorylation of lipids tightly bound to secretory immunoglobulin A in antibody fractions from human breast milk possessing protein kinase activity.
TLDR
The fractions of antibodies (Abs) containing only sIgA and IgG were purified from human breast milk by Protein A-Sepharose chromatography and they catalyzed phosphorylation of casein in the presence of [gamma-32P]ATP, suggesting that phosphorylated polypeptides of different clonal origin are catalyzed by abzymes of differentClonal origin. Expand
The characteristics of antibodies of mice immunized by human unconventional myosin 1c.
TLDR
It is demonstrated that the intraperitoneal administration of murine lymphoma NK/Ly cells in mice immunized with 48 kDa isoform of human blood serum unconventional myosin 1c leads to generation of ascitic fluid that contained specific IgG-antibodies. Expand
...
1
2
...