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- Publications
- Influence
Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slices.
- H. Katsuki, S. Nakai, Y. Hirai, K. Akaji, Y. Kiso, M. Satoh
- Biology, Medicine
- European journal of pharmacology
- 8 June 1990
The effect of recombinant human interleukin 1-beta (IL-1 beta) on long-term potentiation (LTP) in the mossy fiber-CA3 pathway of mouse hippocampal slice preparations was investigated. IL-1 beta… Expand
Novel antioxidative metabolites in rat liver with ingested sesamin.
- M. Nakai, M. Harada, +4 authors Y. Kiso
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 4 February 2003
Sesamin, a major lignan in sesame oil, is known to have many biological activities, especially protective effects against oxidative damage in the liver. As sesamin itself has no antioxidative… Expand
Inhibitory effects of oolong tea polyphenols on pancreatic lipase in vitro.
Fifty-four polyphenols isolated from tea leaves were evaluated for their inhibitory activities against pancreatic lipase, the key enzyme of lipid absorption in the gut. (-)-Epigallocatechin… Expand
Antihypertensive Effect of Angiotensin I-Converting Enzyme Inhibitory Peptides from a Sesame Protein Hydrolysate in Spontaneously Hypertensive Rats
- D. Nakano, Kyoichi Ogura, +13 authors Y. Matsumura
- Chemistry, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 May 2006
Sesame peptide powder (SPP) exhibited angiotensin I-converting enzyme (ACE) inhibitory activity, and significantly and temporarily decreased the systolic blood pressure (SBP) in spontaneously… Expand
Aging of whiskey increases 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity.
- H. Aoshima, Hideaki Tsunoue, H. Koda, Y. Kiso
- Chemistry, Medicine
- Journal of agricultural and food chemistry
- 17 July 2004
1,1-Diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity of Japanese whiskey after various aging periods in oak barrels was measured to evaluate the antioxidative effects of whiskey. The… Expand
Identification of the major antioxidative metabolites in biological fluids of the rat with ingested (+)-catechin and (-)-epicatechin.
- M. Harada, Y. Kan, +5 authors Y. Kiso
- Medicine, Chemistry
- Bioscience, biotechnology, and biochemistry
- 23 June 1999
(+)-Catechin and (-)-epicatechin are known to be biologically effective antioxidants present in the human diet, particularly in wine and tea. We studied the metabolism of these compounds to elucidate… Expand
Possible Role of L-Carnosine in the Regulation of Blood Glucose through Controlling Autonomic Nerves
- K. Nagai, A. Niijima, +5 authors Y. Kiso
- Medicine
- Experimental biology and medicine
- 1 November 2003
Mammalian muscles synthesize L-carnosine, but its roles were unknown. Previously, we found in rats that the administration of a certain amount of L-carnosine elicited an inhibition of the… Expand
Dose-dependent effects of L-carnosine on the renal sympathetic nerve and blood pressure in urethane-anesthetized rats.
- M. Tanida, A. Niijima, +6 authors K. Nagai
- Medicine
- American journal of physiology. Regulatory…
- 1 February 2005
The physiological function of L-carnosine (beta-alanyl-L-histidine) synthesized in mammalian muscles has been unclear. Previously, we observed that intravenous (i.v.) injection of L-carnosine… Expand
Antiallergic Effects of Lactobacillus pentosus Strain S-PT84 Mediated by Modulation of Th1/Th2 Immunobalance and Induction of IL-10 Production
- Y. Nonaka, T. Izumo, +6 authors Y. Kiso
- Biology, Medicine
- International Archives of Allergy and Immunology
- 2007
Background: Many types of fermented food are consumed in Japan. Although some are produced by plant-origin lactic-acid bacteria (LAB) fermentation, the physiological functions of such bacteria remain… Expand
Sesamin Metabolites Induce an Endothelial Nitric Oxide-Dependent Vasorelaxation through Their Antioxidative Property-Independent Mechanisms: Possible Involvement of the Metabolites in the…
- D. Nakano, Chol-Jun Kwak, +9 authors Y. Matsumura
- Chemistry, Medicine
- Journal of Pharmacology and Experimental…
- 1 July 2006
Sesamin, a major lignan in sesame seeds and oil, has been known to lower blood pressure in several types of experimental hypertensive animals. A recent study demonstrated that sesamin metabolites had… Expand