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Fucosylated type‐2 chain polylactosamine antigens in human lung cancer
Four specific monoclonal antibodies (MAbs) have been used to study distributions of fucosylated type‐2 chain polylactosamine antigens, Lex, poly Lex, Ley and sialylated Lex‐i antigens, in human lung
Reversed distribution of calpains and calpastatin in human pituitary gland and selective localization of calpastatin in adrenocorticotropin-producing cells as demonstrated by immunohistochemistry.
These findings indicate that each type of cells producing a specific hormone is equipped with a different balance of the enzyme-inhibitor system involved in the Ca2+-dependent degradation of intracellular proteins.
Historical control data on developmental toxicity studies in rats
Control data from prenatal developmental studies performed in rats from 2011 to 2015 analyzed, finding inter‐laboratory variations in the incidences of fetal anomalies seemed to be due to differences in the selection of observation parameters, observation criteria, and classification of the findings, as well as to Differences in terminology of fetal alterations.
Coumestrol decreases intestinal alkaline phosphatase activity in post-delivery mice but does not affect vitamin D receptor and calcium channels in post-delivery and neonatal mice.
Coumestrol decreased intestinal alkaline phosphatase activity in the small intestines of maternal mice at the level used in the present study, and the mechanisms underlying this effect are different for the jejunum and duodenum.
Effects of coumestrol administration to pregnant and lactating mice on intestinal alkaline phosphatase activity
Cummestrol administration during pregnancy may decrease the mRNA expression of IAP and the ALP activity in the intestine of the pre‐delivery mice through ERα, but coumestrol had little effect on intestinal ALP activity at 10 days after parturition.
Repairability of skeletal alterations induced by sodium valproate in rats
In pups, however, discontinued rib cartilage was not observed, and the incidence of a short supernumerary rib was significantly lower than that in the fetuses, suggesting that these alterations are postnatally repairable.