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STAT3 regulates arginase-I in myeloid-derived suppressor cells from cancer patients.
Myeloid-derived suppressor cells (MDSC) play a key immunosuppressive role in various types of cancer, including head and neck squamous cell carcinoma (HNSCC). In this study, we characterizedExpand
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A method for calling gains and losses in array CGH data.
Array CGH is a powerful technique for genomic studies of cancer. It enables one to carry out genome-wide screening for regions of genetic alterations, such as chromosome gains and losses, orExpand
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STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade
  • J. Fu, D. Kanne, +16 authors Y. Kim
  • Biology, Medicine
  • Science Translational Medicine
  • 15 April 2015
Cyclic dinucleotide formulated cancer vaccine combined with PD-1 blockade can induce regression of tumors that do not express PD-L1 constitutively. A therapy that STINGs tumors Stimulator ofExpand
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Determinants of Organizational Citizenship Behavior and Its Outcomes
Introduction Today, changes in organizational environments, their resultant innovations, and flexibility are emphasized, which necessarily calls for voluntary behavior from members of anExpand
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An introductory characterization of a combat-casualty-care relevant swine model of closed head injury resulting from exposure to explosive blast.
Explosive blast has been extensively used as a tactical weapon in Operation Iraqi Freedom (OIF) and more recently in Operation Enduring Freedom(OEF). The polytraumatic nature of blast injuries isExpand
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Push-pull tests for assessing in situ aerobic cometabolism.
Three types of single-well push-pull tests were developed for use in assessing the feasibility of in situ aerobic cometabolism of chlorinated aliphatic hydrocarbons (CAHs). These included transportExpand
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Experimental investigation of a spiral-wound pressure-retarded osmosis membrane module for osmotic power generation.
Pressure-retarded osmosis (PRO) uses a semipermeable membrane to produce renewable energy from salinity-gradient energy. A spiral-wound (SW) design is one module configuration of the PRO membrane.Expand
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Development of Computer-Aided Inspection System with CMM for Integrated Mold Manufacturing
An interactive and integrated inspection system has been developed for molds having sculptured surfaces with some basic features, such as; holes, slots and bosses. Features to be inspected can beExpand
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Down-regulation of SNAIL suppresses MIN mouse tumorigenesis: modulation of apoptosis, proliferation, and fractal dimension.
OBJECTIVES Emerging evidence implicates the SNAIL family of transcriptional repressors in cancer development; however, the role of SNAIL in colorectal cancer has not been established. To investigateExpand
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