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Protocol issues for delayed Gd(DTPA)2–‐enhanced MRI (dGEMRIC) for clinical evaluation of articular cartilage
Biochemical and histologic data have validated the technique of delayed gadolinium‐enhanced MRI, in which the T1 values of cartilage after penetration of Gd(DTPA)2–allow assessment of the… Expand
The Cdc42 GTPase-associated proteins Gic1 and Gic2 are required for polarized cell growth in Saccharomyces cerevisiae.
BEM2 of Saccharomyces cerevisiae encodes a Rho-type GTPase-activating protein that is required for proper bud site selection at 26 degrees C and for bud emergence at elevated temperatures. We show… Expand
Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues.
Mesenchymal stem cells (MSCs), which evoke only minimal immune reactivity, may have anti-inflammatory and immunomodulatory effects. In this study, we conducted a comparative analysis of the… Expand
Hydrogen Peroxide Generation by the Pepper Extracellular Peroxidase CaPO2 Activates Local and Systemic Cell Death and Defense Response to Bacterial Pathogens1[W][OA]
Reactive oxygen species (ROS) are responsible for mediating cellular defense responses in plants. Controversy has existed over the origin of ROS in plant defense. We have isolated a novel… Expand
Two Distinct Pseudomonas Effector Proteins Interact with the Pto Kinase and Activate Plant Immunity
The Pto serine/threonine kinase of tomato confers resistance to speck disease by recognizing strains of Pseudomonas syringae that express the protein AvrPto. Pto and AvrPto physically interact, and… Expand
The Drosophila gene rbp9 encodes a protein that is a member of a conserved group of putative RNA binding proteins that are nervous system-specific in both flies and humans
The rbp9 gene of Drosophila melanogaster has been molecularly characterized and shown to be expressed solely in the CNS, where it encodes proteins with three RNA recognition motifs (RRMs). Sequencing… Expand
Crystallographic and Mutational Analysis of the CD40-CD154 Complex and Its Implications for Receptor Activation*
- Hyun-jung An, Y. Kim, +6 authors Hayyoung Lee
- Biology, Medicine
- The Journal of Biological Chemistry
- 1 February 2011
CD40 is a tumor necrosis factor receptor (TNFR) family protein that plays an important role in B cell development. CD154/CD40L is the physiological ligand of CD40. We have determined the crystal… Expand
Overexpression of Pto Activates Defense Responses and Confers Broad Resistance
The tomato disease resistance (R) gene Pto specifies race-specific resistance to the bacterial pathogen Pseudomonas syringae pv tomato carrying the avrPto gene. Pto encodes a serine/threonine protein… Expand
Automated cardiovascular magnetic resonance image analysis with fully convolutional networks
- Wenjia Bai, M. Sinclair, +20 authors D. Rueckert
- Computer Science, Medicine
- Journal of Cardiovascular Magnetic Resonance
- 25 October 2017
We demonstrate an automated analysis method for CMR images, which is based on a fully convolutional network (FCN). Expand
Sex-lethal, master and slave: a hierarchy of germ-line sex determination in Drosophila.
Female sex determination in the germ line of Drosophila melanogaster is regulated by genes functioning in the soma as well as genes that function within the germ line. Genes known or suspected to be… Expand