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Association of ALDH2 polymorphism with sensitivity to acetaldehyde-induced micronuclei and facial flushing after alcohol intake.
To investigate whether sensitivity to the induction of micronuclei by acetaldehyde is associated with genetic polymorphisms of the aldehyde dehydrogenase-2 (ALDH2) gene, cytokinesis-blockExpand
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Cytotoxicity of honeybee (Apis mellifera) venom in normal human lymphocytes and HL-60 cells.
Whole bee venom (BV) is used to treat inflammatory diseases in Korean traditional medicine. Various studies have demonstrated anti-inflammatory and anticancer effects of BV. The toxicity ofExpand
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Genotoxic effects of 3 T magnetic resonance imaging in cultured human lymphocytes.
The clinical and preclinical use of high-field intensity (HF, 3 T and above) magnetic resonance imaging (MRI) scanners have significantly increased in the past few years. However, potential healthExpand
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Effect of Bupleuri Radix extracts on the toxicity of 5-fluorouracil in HepG2 hepatoma cells and normal human lymphocytes.
Despite the excellent chemotherapeutic effect of 5-fluorouracil, its cytotoxicity and genotoxicity in normal cells remain a major problem. We sought to assess whether Bupleuri Radix extract enhancesExpand
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Association of the NQO1, MPO, and XRCC1 Polymorphisms and Chromosome Damage Among Workers at a Petroleum Refinery
Benzene is a leukemogen, and exposure to benzene is an occupational hazard in the petroleum refining industries. The effects of genetic polymorphisms in the NQO1 (rs1800566), MPO (rs2333227), andExpand
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Comparative studies on the genotoxicity and cytotoxicity of polymeric gene carriers polyethylenimine (PEI) and polyamidoamine (PAMAM) dendrimer in Jurkat T-cells
A safe alternative to the viral system used in gene therapy is a nonviral gene delivery system. Although polyethylenimine (PEI) and polyamidoamine (PAMAM) dendrimer are among the most promisingExpand
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Enhancement of cisplatin cytotoxicity by benzyl isothiocyanate in HL-60 cells.
Cis-diamminedichloroplatinum (II) (cisplatin) is one of the most widely used chemotherapeutic drugs, but its effectiveness is limited by tumor cell resistance and the severe side effects it causes.Expand
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Radiation-induced changes in DNA methylation and their relationship to chromosome aberrations in nuclear power plant workers
  • Younghyun Lee, Y. Kim, +4 authors H. Chung
  • Medicine, Biology
  • International journal of radiation biology
  • 30 January 2015
Abstract Purpose: We investigated the association between occupational radiation exposure and DNA methylation changes in nuclear power plant workers. We also evaluated whether radiation- induced DNAExpand
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Micronucleus-centromere assay and DNA repair gene polymorphism in lymphocytes of industrial radiographers.
The micronucleus-centromere assay using a pan-centromeric probe was used to assess chromosomal damage in lymphocytes of 47 industrial radiographers occupationally exposed to low dose ionizingExpand
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Protective Effect of Onion Extract on Bleomycin-Induced Cytotoxicity and Genotoxicity in Human Lymphocytes
  • Y. Cho, J. W. Lee, +6 authors H. Chung
  • Biology, Medicine
  • International journal of environmental research…
  • 1 February 2016
Following one of the world’s largest nuclear accidents, occured at Fukushima, Japan in 2011, a significant scientific effort has focused on minimizing the potential adverse health effects due toExpand
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