• Publications
  • Influence
Two Distinct Pools of Synaptic Vesicles in Single Presynaptic Boutons in a Temperature-Sensitive Drosophila Mutant, shibire
In a temperature-sensitive Drosophila mutant, shibire, synaptic vesicles are completely depleted in nerve terminals after stimulation at 34 degrees C, but upon returning to 22 degrees C, endocytosisExpand
  • 278
  • 29
Size of Vesicle Pools, Rates of Mobilization, and Recycling at Neuromuscular Synapses of a Drosophila mutant, shibire
Two vesicle pools, readily releasable (RRP) and reserve (RP) pools, are present at Drosophila neuromuscular junctions. Using a temperature-sensitive mutant, shibire(ts), we studied pool sizes andExpand
  • 193
  • 16
Distinct Requirements for Evoked and Spontaneous Release of Neurotransmitter Are Revealed by Mutations in theDrosophila Gene neuronal-synaptobrevin
Two modes of vesicular release of transmitter occur at a synapse: spontaneous release in the absence of a stimulus and evoked release that is triggered by Ca2+ influx. These modes often have beenExpand
  • 233
  • 14
  • PDF
Action potentials in the rat chromaffin cell and effects of acetylcholine.
1. Electrophysiological properties of the rat chromaffin cell were studied using intracellular recording techniques. 2. The resting potential in the chromaffin cell was ‐49 +/‐ 6 mV (mean +/‐ S.D., nExpand
  • 286
  • 13
Tetanic Stimulation Recruits Vesicles from Reserve Pool via a cAMP-Mediated Process in Drosophila Synapses
At Drosophila neuromuscular junctions, there are two synaptic vesicle pools, namely the exo/endo cycling pool (ECP) and the reserve pool (RP). We studied the recruitment process from RP using aExpand
  • 178
  • 12
Selective Replenishment of Two Vesicle Pools Depends on the Source of Ca2+ at the Drosophila Synapse
After synaptic vesicles (SVs) undergo exocytosis, SV pools are replenished by recycling SVs at nerve terminals. At Drosophila neuromuscular synapses, there are two distinct SV pools (i.e., theExpand
  • 94
  • 11
Analysis of Conditional Paralytic Mutants in Drosophila Sarco-Endoplasmic Reticulum Calcium ATPase Reveals Novel Mechanisms for Regulating Membrane Excitability
Individual contributions made by different calcium release and sequestration mechanisms to various aspects of excitable cell physiology are incompletely understood. SERCA, a sarco-endoplasmicExpand
  • 71
  • 11
  • PDF
A clock gene, period, plays a key role in long-term memory formation in Drosophila.
The cAMP-responsive transcription factor, CREB, is required for formation of long-term memory (LTM) in Drosophila melanogaster and regulates transcription of a circadian clock gene, period (per).Expand
  • 129
  • 8
  • PDF
Aggressive behaviours of female Drosophila melanogaster are influenced by their social experience and food resources
Abstract Aggressive behaviours of female Drosophila melanogaster (Meigen) (Diptera: Drosophilidae) were studied in the laboratory. These behaviours included ‘approach’, a seemingly intentionalExpand
  • 77
  • 8
Chromaffin cell action potentials and their possible role in adrenaline secretion from rat adrenal medulla.
1. The role of action potentials in adrenaline secretion was investigated in the rat adrenal medulla. The effects of various treatments on adrenaline secretion from the perfused adrenal medulla wereExpand
  • 171
  • 7
...
1
2
3
4
5
...