Share This Author
Stimulatory effect of curcumin on osteoclast apoptosis.
Expression of monocyte chemoattractant protein 1 (MCP-1) in adult periodontal disease: increased monocyte chemotactic activity in crevicular fluids and induction of MCP-1 expression in gingival…
Gingival fibroblasts can participate in monocyte recruitment in gingival tissues of adult periodontal patients via the M CP-1 gene product and that MCP-1 plays an important role in the inflammatory reaction in the disease.
Prostaglandin E2 stimulates osteoclast formation via endogenous IL-1 beta expressed through protein kinase A.
- S. Amano, K. Naganuma, Y. Kawata, K. Kawakami, S. Kitano, S. Hanazawa
- Biology, MedicineJournal of immunology
- 1 March 1996
The present study found that endogenous IL-6 is partially involved in PGE2-stimulated osteoclast formation and induced IL-1 beta gene expression in the primed calvarial cells from mouse embryos.
Porphyromonas gingivalis fimbriae stimulate bone resorption in vitro
The present data demonstrate that P. gingivalis fimbriae stimulate bone resorption in vitro via the generation of an inflammatory cytokine(s) and these cytokines were markedly expressed in the fimbria-treated calvarial bone cells.
An assay system utilizing devitalized bone for assessment of differentiation of osteoclast progenitors
- S. Amano, S. Hanazawa, Y. Kawata, K. Ohta, H. Kitami, S. Kitano
- BiologyJournal of bone and mineral research : the…
- 1 March 1992
Results suggest that osteoclast progenitors in the mouse calvarial population examined differentiated into mature osteoclasts in the presence of 1α,25‐(OH)2D3 on devitalized bone slices.
Porphyromonas gingivalis fimbria-stimulated bone resorption in vitro is inhibited by a tyrosine kinase inhibitor
Genistein, a potent inhibitor of tyrosine kinase, markedly inhibited bone resorption stimulated by the fimbriae, and inhibited induction of several tyrosinesine-phosphorylated proteins in thefimbria-treated calvarial bone cells from mouse embryos.
A gamma Gly-268 to Glu substitution is responsible for impaired fibrin assembly in a homozygous dysfibrinogen Kurashiki I.
The gamma Glu-268 substitution newly identified in this homozygous dysfibrinogen seems to impair proper alignment of adjacent D domains of neighboring fibrin molecules in the double-stranded fibr in protofibril, resulting in delayed fibrIn gel formation.
Transforming growth factor-beta-induced gene expression of monocyte chemoattractant JE in mouse osteoblastic cells, MC3T3-E1.
A new type of Ser substitution for gamma Arg-275 in fibrinogen Kamogawa I characterized by impaired fibrin assembly.
A new type of substitution, Arg to Ser at gamma275, has been found in a heterozygous dysfibrinogen derived from a 23-year-old woman with no major bleeding or thrombosis, and the structural derangement that affects the D:D association may not be so severe as compared with those of Cys and His mutants.
Expression of plasminogen activator inhibitor 2 in the adult and embryonic mouse tissues.
- Y. Kawata, J. Mimuro, M. Kaneko, K. Shimada, Y. Sakata
- BiologyThrombosis and haemostasis
- 1 October 1996
The data suggest that PAI-2 may play a role in protecting the mouse embryo from the protease attack in the amniotic fluid and also in maintaining and/or protecting the structure of various surfaces in the mouse.