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- Publications
- Influence
The CREB Coactivator TORC2 Functions as a Calcium- and cAMP-Sensitive Coincidence Detector
- R. Screaton, M. D. Conkright, +9 authors M. Montminy
- Biology, Medicine
- Cell
- 1 October 2004
Elevations in circulating glucose and gut hormones during feeding promote pancreatic islet cell viability in part via the calcium- and cAMP-dependent activation of the transcription factor CREB.… Expand
Silencing the constitutive active transcription factor CREB by the LKB1‐SIK signaling cascade
- Y. Katoh, H. Takemori, +10 authors M. Okamoto
- Chemistry, Medicine
- The FEBS journal
- 1 June 2006
Cyclic AMP responsive element (CRE)‐binding protein (CREB) is known to activate transcription when its Ser133 is phosphorylated. Two independent investigations have suggested the presence of… Expand
Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm.
- Y. Katoh, H. Takemori, +4 authors M. Okamoto
- Biology, Medicine
- European journal of biochemistry
- 1 November 2004
Salt-inducible kinase-1 (SIK1) is phosphorylated at Ser577 by protein kinase A in adrenocorticotropic hormone-stimulated Y1 cells, and the phospho-SIK1 translocates from the nucleus to the cytoplasm.… Expand
Salt-inducible kinase (SIK) isoforms: their involvement in steroidogenesis and adipogenesis
- Y. Katoh, H. Takemori, N. Horike, J. Doi, M. Okamoto
- Biology, Medicine
- Molecular and Cellular Endocrinology
- 31 March 2004
The cloning of salt-inducible kinase-1 (SIK1) that was specifically expressed in the adrenal glands of high-salt diet-fed rats led to subsequent cloning of adipose-specific SIK2 and rather ubiquitous… Expand
ACTH-induced Nucleocytoplasmic Translocation of Salt-inducible Kinase
- H. Takemori, Y. Katoh, N. Horike, J. Doi, M. Okamoto
- Biology, Medicine
- The Journal of Biological Chemistry
- 1 November 2002
Salt-inducible kinase (SIK), a serine/threonine protein kinase expressed at an early stage of adrenocorticotropic hormone (ACTH) stimulation in Y1 mouse adrenocortical tumor cells, repressed the… Expand
Characterization of the adrenal-specific antigen IZA (inner zone antigen) and its role in the steroidogenesis
- L. Min, H. Takemori, Y. Nonaka, Y. Katoh, M. Okamoto
- Biology, Medicine
- Molecular and Cellular Endocrinology
- 27 February 2004
Inner zone antigen (IZA) is a protein specifically expressed in the zona fasciculata and reticularis of the adrenal cortex. The cDNA encoding IZA was found to be identical to that encoding the… Expand
Salt-inducible kinase is involved in the ACTH/cAMP-dependent protein kinase signaling in Y1 mouse adrenocortical tumor cells.
- X. Lin, H. Takemori, +5 authors M. Okamoto
- Biology, Medicine
- Molecular endocrinology
- 1 August 2001
The involvement of salt-inducible kinase, a recently cloned protein serine/threonine kinase, in adrenal steroidogenesis was investigated. When Y1 mouse adrenocortical tumor cells were stimulated by… Expand
Salt-inducible kinase in steroidogenesis and adipogenesis
- M. Okamoto, H. Takemori, Y. Katoh
- Biology, Medicine
- Trends in Endocrinology & Metabolism
- 29 February 2004
The salt-inducible kinases (SIKs) are a family of related serine-threonine kinases. In cultured adrenocortical cells, SIK1 is rapidly but transiently induced by adrenocorticotropin (ACTH) treatment,… Expand
Histamine production by cultured microglial cells of the mouse
- Y. Katoh, M. Niimi, Y. Yamamoto, Tomohiro Kawamura, A. Yamatodani
- Biology, Medicine
- Neuroscience Letters
- 15 June 2001
We previously reported that cells other than mast cells or neurons could synthesize histamine in response to lipopolysaccharide (LPS) or interleukin 1beta in the rat brain. To identify the… Expand
Salt-inducible Kinase Represses cAMP-dependent Protein Kinase-mediated Activation of Human Cholesterol Side Chain Cleavage Cytochrome P450 Promoter through the CREB Basic Leucine Zipper Domain*
- J. Doi, H. Takemori, Xing-zi Lin, N. Horike, Y. Katoh, M. Okamoto
- Biology, Medicine
- The Journal of Biological Chemistry
- 3 May 2002
Salt-inducible kinase (SIK), one of the serine/threonine protein kinases, was transiently expressed in Y1 cells during the early phase of the ACTH/cAMP-dependent protein kinase (PKA)-mediated signal… Expand