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Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in
BACKGROUND T(H)2 cells and eosinophils selectively express CC chemokine receptor 4 and CCR3, respectively, and their chemokine ligands are likely to play important roles in the pathogenesis of atopicExpand
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Chemokine production by the BEAS-2B human bronchial epithelial cells: differential regulation of eotaxin, IL-8, and RANTES by TH2- and TH1-derived cytokines.
BACKGROUND Bronchial epithelial cells produce many types of chemokines and may contribute to lung inflammation by recruiting inflammatory cells. The CC chemokine eotaxin is a potent,Expand
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Cross talk of the interferon-alpha/beta signalling complex with gp130 for effective interleukin-6 signalling.
BACKGROUND Signalling cross talk provides a molecular basis for modulating a given signalling pathway by another, and it is often critical for regulating cellular responses elicited by cytokines.Expand
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Acacetin inhibits expression of E-selectin on endothelial cells through regulation of the MAP kinase signaling pathway and activation of NF-κB
Abstract Since E-selectin-mediated adhesion of leukocytes or tumor cells to the vascular endothelium is a key early event in the initiation of inflammatory response and cancer metastasis, E-selectinExpand
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Significance of the eosinophil cationic protein/eosinophil count ratio in asthmatic patients: its relationship to disease severity.
BACKGROUND Serum levels of eosinophil cationic protein (ECP) may reflect the degree of bronchial inflammation in patients with asthma, but its clinical value as a parameter for monitoring asthmaExpand
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Diagnostic value of mitotic activity in endometrial stromal sarcoma: report of two cases.
Two patients with endometrial stromal neoplasms, one low-grade and one high-grade malignant stromal sarcomas, were treated. The tumor cells of these two sarcomas had many common cytologic featuresExpand
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Synergistic Effect of Theophylline and Procaterol On Interleukin-5-Induced Degranulation from Human Eosinophils
Inhibiting the release of toxic granule proteins from eosinophils is a possible means of treating allergic inflammation. This study was performed to examine whether procaterol and theophylline,Expand
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Chemokines induce eosinophil degranulation through CCR-3.
BACKGROUND Such CC chemokines as eotaxin and RANTES induce preferential eosinophil recruitment in allergic inflammation. They also elicit proinflammatory effector functions of eosinophils, such asExpand
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Serum measurement of thymus and activation-regulated chemokine/CCL17 in children with atopic dermatitis: elevated normal levels in infancy and age-specific analysis in atopic dermatitis.
Elevated blood levels of thymus and activation-regulated chemokine (TARC)/CCL17 have been observed in atopic dermatitis (AD) and may serve as a new biomarker for AD. However, the normal levels,Expand
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Matrix Metalloproteinase-9 in Peripheral Blood Eosinophils
Background: Matrix metalloproteinases (MMPs) are major contributors to tumor invasion, remodeling of connective tissue and infiltration of inflammatory cells and may be important mediators inExpand
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