Determination and bioimaging method for nitric oxide in biological specimens by diaminofluorescein fluorometry.
The present novel diaminofluorescein fluorometry should be useful not only for sensitive NO assay, but also for NO imaging in a variety of biological specimens.
Protection by a radical scavenger edaravone against cisplatin-induced nephrotoxicity in rats.
- K. Sueishi, Kazuto Mishima, R. Oishi
- Biology, MedicineEuropean Journal of Pharmacology
- 13 September 2002
A simple and simultaneous determination of acyclovir and ganciclovir in human plasma by high-performance liquid chromatography.
- D. Teshima, K. Otsubo, Tsuneko Yoshida, Y. Itoh, R. Oishi
- ChemistryBiomedical chromotography
- 1 December 2003
A simple high-performance liquid chromatographic method was developed for the simultaneous determination of the therapeutic levels of acyclovir and ganciclovir in human plasma and is applicable to therapeutic monitoring during antiviral medication.
Protective effect of cyclic AMP against cisplatin-induced nephrotoxicity.
- Kazuto Mishima, A. Baba, M. Matsuo, Y. Itoh, R. Oishi
- Biology, ChemistryFree Radical Biology & Medicine
- 1 May 2006
Blockade of voltage-sensitive sodium channels by NS-7, a novel neuroprotective compound, in the rat brain
- T. Shimidzu, Y. Itoh, K. Kimura
- Biology, ChemistryNaunyn-Schmiedeberg's Archives of Pharmacology
- 15 April 1997
The results suggest that the blockade of neurotoxin receptor site 2 of VSSC in the brain contributes to the neuroprotective action of NS-7.
Amphotericin B-Induced Renal Tubular Cell Injury Is Mediated by Na+ Influx through Ion-Permeable Pores and Subsequent Activation of Mitogen-Activated Protein Kinases and Elevation of Intracellular…
It is suggested that Na+ entry through membrane pores formed by the association of AMB with membrane cholesterol leads to the activation of MAP kinases and the elevation of the intracellular Ca2+ concentration, leading to renal tubular cell injury.
Involvement of de novo ceramide synthesis in radiocontrast-induced renal tubular cell injury.
It is demonstrated here for the first time that the enhancement of de novo ceramide synthesis contributes to radiocontrast nephropathy.
Characterization of Histamine Release from the Rat Hypothalamus as Measured by In Vivo Microdialysis
- Y. Itoh, R. Oishi, M. Nishibori, K. Saeki
- Biology, MedicineJournal of Neurochemistry
- 1 March 1991
The results suggest that both HA‐N‐methyltransferase and H3 autoreceptors are involved in maintaining a constant level of extracellular HA and that their blockade effectively results in a higher activity level of the endogenous histaminergic system in the CNS.
Neuronal histamine inhibits methamphetamine-induced locomotor hyperactivity in mice
- Y. Itoh, M. Nishibori, R. Oishi, K. Saeki
- Biology, PsychologyNeuroscience Letters
- 10 August 1984
Clinical and experimental evidence for prevention of acute renal failure induced by radiographic contrast media.
It is shown that caspase-dependent apoptosis is an important factor in the pathogenesis of radiocontrast nephropathy and clarified cellular mechanisms underlying the radiOContrast media-induced apoptosis.
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