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An insulin-releasing system that is responsive to glucose
Abstract A membrane system consisting of poly(acrylic acid)-grafted porous cellulose film and glucose oxidase was synthesized for insulin delivery in response to glucose concentration. The principleExpand
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pH-Sensitive Gating by Conformational Change of a Polypeptide Brush Grafted onto a Porous Polymer Membrane
Benzyl glutamate NCA was graft-polymerized onto a porous poly(tetrafluoroethylene) membrane in order to study the effects of pH and ionic strength on permeation rate. The membrane was firstExpand
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Patterned immobilization of thermoresponsive polymer
The thermoresponsive polymer poly(N-isopropylacrylamide) was immobilized in a specific pattern on a polystyrene matrix by photolithography. N-Isopropylacrylamide was copolymerized with acrylic acid.Expand
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In vitro selection of a ligase ribozyme carrying alkylamino groups in the side chains.
A novel ligase ribozyme was in vitro selected from a random-sequence RNA library including N(6)-aminohexyl-modified adenine residues in place of natural adenine residues. This ribozyme mediated theExpand
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Photocontrolled Gating by Polymer Brushes Grafted on Porous Glass Filter
Polymethacrylate-containing spiropyran was grafted on a glass filter to control permeation of organic liquid by photoirradiation. The glass filter was at first coupled withExpand
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A case of phosphaturic mesenchymal tumour (mixed connective tissue variant) that developed in the subcutaneous tissue of a patient with oncogenic osteomalacia and produced fibroblast growth factor 23
frontotemporal region of the scalp. The lesions are usually recognized within the first few years of life, and are nonscarring, permanent, and not associated with neurological deficit. There is oneExpand
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Recent developments in olefin polymerizations with transition metal catalysts
Abstract Discovery of effective homogeneous transition metal catalysts for olefin polymerization must be one of the most dramatic technologies for polymer synthesis in the 1980s. Especially,Expand
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Peroxidase activity of in vitro-selected 2'-amino RNAs.
Peroxidase activities of RNAs containing 2'-amino groups, which were selected as aptamers binding to N-methylmesoporphyrin IX, were investigated. Some clones promoted the oxidation reaction ofExpand
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In vitro adaptation of a ligase ribozyme for activity under a low-pH condition.
A ligase ribozyme accelerating a ligation reaction with oligonucleotide under a low-pH condition was selected by in vitro adaptation. A ribozyme active at pH 7 was randomly mutated, and the resultantExpand
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