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Nonspecific cross-reacting antigen-50/90 (NCA-50/90) as a new tumor marker.
- M. Kuroki, H. Matsushita, H. Matsumoto, Y. Hirose, T. Senba, T. Yamamoto
- Anticancer research
- 1 November 1999
BACKGROUND The nonspecific cross-reacting antigen-50/90 (NCA-50/90) is a glycoprotein antigen which shares some antigenic determinants with carcinoembryonic antigen (CEA). No definite clinical value… Expand
Retinoic acid syndrome in NOD/scid mice induced by injecting an acute promyelocytic leukemia cell line
All-trans retinoic acid (ATRA) induces complete remission in patients with acute promyelocytic leukemia (APL). However, ATRA sometimes causes retinoic acid syndrome (RAS) characterized by respiratory… Expand
A developmental study of interphotoreceptor retinoid-binding protein (IRBP) in single and double homozygous rd and rds mutant mouse retinae.
- T. van Veen, P. Ekstrom, +4 authors G. Chader
- Biology, Medicine
- Experimental eye research
- 1 August 1988
Interphotoreceptor retinoid-binding protein (IRBP) was studied using immunochemical and immunocytochemical techniques in retinae of mice with allelic combinations at the rd and rds loci at different… Expand
Carbon coating of anatase-type TiO2 through their precipitation in PVA aqueous solution
Abstract Fine particles of photocatalytic anatase-type TiO2 prepared through hydrolysis of titanium-tetraisopropoxide were coated by carbon through their precipitation in poly(vinyl alcohol) (PVA)… Expand
Immunotherapy and gene therapy of cancer using antibodies or their genes against tumor-associated antigens.
The purpose of this article is to review the current significance of anti-tumor-associated antigen (TAA) antibodies in the therapy of cancer. Current data suggest that antibodies or their genes… Expand
Immune-related zinc finger gene ZFAT is an essential transcriptional regulator for hematopoietic differentiation in blood islands
- T. Tsunoda, Yasuo Takashima, +9 authors S. Shirasawa
- Biology, Medicine
- Proceedings of the National Academy of Sciences
- 26 July 2010
TAL1 plays pivotal roles in vascular and hematopoietic developments through the complex with LMO2 and GATA1. Hemangioblasts, which have a differentiation potential for both endothelial and… Expand
Generation, immunologic characterization and antitumor effects of human monoclonal antibodies for carcinoembryonic antigen
- T. Imakiire, M. Kuroki, +9 authors M. Kuroki
- Medicine, Biology
- International journal of cancer
- 10 February 2004
We generated fully human mAbs (HmAbs) to carcinoembryonic antigen (CEA) using the KM mouse, which carries a human chromosome 14 fragment containing the entire Ig H chain loci and human κ L chain… Expand
Establishment of a CD4-positive plasmacytoma cell line (AMO1).
A human plasmacytoma cell line (AMO1) was established. The AMO1 cells had the light and electron microscopic characteristics typical of plasmacytoma cells and did not harbor Epstein-Barr virus. These… Expand
Tumor growth suppression by a retroviral vector displaying scFv antibody to CEA and carrying the iNOS gene.
BACKGROUND In a recent in vitro study we demonstrated a specifically-targeted killing of CEA-expressing cells by a recombinant bifunctional retrovector displaying an scFv antibody to CEA and carrying… Expand
Effect of Fluconazole on the Pharmacokinetics and Pharmacodynamics of Oral and Rectal Bromazepam: An Application of Electroencephalography as the Pharmacodynamic Method
- Y. Ohtani, T. Kotegawa, K. Tsutsumi, T. Morimoto, Y. Hirose, S. Nakano
- Journal of clinical pharmacology
- 1 February 2002
Quantitative analysis of electroencephalography (EEG) is used increasingly to evaluate the pharmacodynamics of benzodiazepines. The present study aimed to apply the EEG method as well as more… Expand