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Combinatorial curvature for planar graphs
- Y. Higuchi
- 1 December 2001
Regarding an infinite planar graph G as a discrete analogue of a noncompact simply connected Riemannian surface, we introduce the combinatorial curvature of G corresponding to the sectional curvature… Expand
A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of K+ channels at the cell surface.
Small-molecule stabilization of protein-protein interactions is an emerging field in chemical biology. We show how fusicoccanes, originally identified as fungal toxins acting on plants, promote the… Expand
Spectral and asymptotic properties of Grover walks on crystal lattice
We propose a twisted Szegedy walk for estimating the limit behavior of a discrete-time quantum walk on a crystal lattice, an infinite abelian covering graph, whose notion was introduced by .… Expand
SPECTRAL GEOMETRY OF CRYSTAL LATTICES
The aim of this expository article is to exhibit several interesting interactions among geometry, graph theory and probability through a brief survey of a series of our recent work on geometry of… Expand
Multicenter phase II study of nivolumab in Japanese patients with relapsed or refractory classical Hodgkin lymphoma
Overexpression of programmed death‐1 (PD‐1) ligands contributes to an immunosuppressive microenvironment. Nivolumab is a PD‐1‐blocking antibody that inhibits the PD‐1 pathway and showed good efficacy… Expand
Specific Direct Small Molecule p300/β-Catenin Antagonists Maintain Stem Cell Potency.
- Y. Higuchi, C. Nguỹên, Shin-ya Yasuda, M. McMillan, K. Hasegawa, M. Kahn
- Biology, Medicine
- Current molecular pharmacology
- 31 July 2016
Despite their high degree of identity and even higher homology, the two Kat3 transcriptional coactivators, CBP and p300, have distinct functions, particularly within the Wnt/β-catenin signaling… Expand
Spectral structure of the Laplacian on a covering graph
In this paper we study the spectral structure of the discrete Laplacian on an infinite graph. We show that, for a finite graph including a certain kind of a family of cycles, the spectrum of the… Expand
Dynamical system induced by quantum walk.
We consider the Grover walk model on a connected finite graph with two infinite length tails and we set an $\ell^\infty$-infinite external source from one of the tails as the initial state. We show… Expand
Identification and functional analysis of brassicicene C biosynthetic gene cluster in Alternaria brassicicola.
- A. Minami, N. Tajima, +4 authors T. Dairi
- Biology, Medicine
- Bioorganic & medicinal chemistry letters
- 1 February 2009
The biosynthetic gene cluster of brassicicene C was identified in Alternaria brassicicola strain ATCC 96836 from genome database search. In vivo and in vitro study clearly revealed the function of… Expand