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EyeCi: Optical clearing and imaging of immunolabeled mouse eyes using light‐sheet fluorescence microscopy
EyeCi enables the visualization of ocular and retinal vasculature in the intact mouse eye by means of light‐sheet fluorescence microscopy. Expand
Retinal S-opsin dominance in Ansell’s mole-rats (Fukomys anselli) is a consequence of naturally low serum thyroxine
Mammals usually possess a majority of medium-wavelength sensitive (M-) and a minority of short-wavelength sensitive (S-) opsins in the retina, enabling dichromatic vision. Unexpectedly, subterraneanExpand
Unusual Ratio between Free Thyroxine and Free Triiodothyronine in a Long-Lived Mole-Rat Species with Bimodal Ageing
Ansell's mole-rats (Fukomys anselli) are subterranean, long-lived rodents, which live in eusocial families, where the maximum lifespan of breeders is twice as long as that of non-breeders. TheirExpand
Higher resting metabolic rate in long-lived breeding Ansell’s mole-rats (Fukomys anselli)
BackgroundReproduction is an energetically expensive process that supposedly impairs somatic integrity in the long term, because resources are limited and have to be allocated between reproductionExpand
Age-Dependent Changes of Monocarboxylate Transporter 8 Availability in the Postnatal Murine Retina
The thyroid hormones (TH) triiodothyronine (T3) and its prohormone thyroxine (T4) are crucial for retinal development and function, and increasing evidence points at TH dysregulation as a cause forExpand
Temperature preferences of African mole-rats (family Bathyergidae).
Many animals are able to detect small temperature differences and show strong temperature preferences during periods of rest and activity. Mammals inhabiting the subterranean ecotope can adapt theirExpand
Audiograms of three subterranean rodent species (genus Fukomys) determined by auditory brainstem responses reveal extremely poor high-frequency cut-offs
ABSTRACT Life underground has shaped the auditory sense of subterranean mammals, shifting their hearing range to low frequencies. Mole-rats of the genus Fukomys have, however, been suggested to hearExpand
Higher gene expression stability during aging in long-lived giant mole-rats than in short-lived rats
Many aging-associated physiological changes are known to occur in short- and long-lived species with different trajectories. Emerging evidence suggests that numerous life history trait differencesExpand
Surprisingly long survival of premature conclusions about naked mole‐rat biology
Naked mole‐rats express many unusual traits for such a small rodent. Their morphology, social behaviour, physiology, and ageing have been well studied over the past half‐century. Many early findingsExpand