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Vasodilatory mechanisms in contracting skeletal muscle.
Skeletal muscle blood flow is closely coupled to metabolic demand, and its regulation is believed to be mainly the result of the interplay of neural vasoconstrictor activity and locally derivedExpand
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Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle.
The metabolic role of 5'AMP-activated protein kinase (AMPK) in regulation of skeletal muscle metabolism in humans is unresolved. We measured isoform-specific AMPK activity and beta-acetyl-CoAExpand
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Resveratrol blunts the positive effects of exercise training on cardiovascular health in aged men
•  In rodents, resveratrol has been shown to enhance training‐induced changes in cardiovascular function, exercise performance and the retardation of atherosclerosis. We examined the effect of 8Expand
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Formation of hydrogen peroxide and nitric oxide in rat skeletal muscle cells during contractions.
We examined intra- and extracellular H(2)O(2) and NO formation during contractions in primary rat skeletal muscle cell culture. The fluorescent probes DCFH-DA/DCFHExpand
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Exercise‐induced hyperaemia and leg oxygen uptake are not altered during effective inhibition of nitric oxide synthase with NG‐nitro‐l‐arginine methyl ester in humans
1 In the present study the highly potent nitric oxide synthase (NOS) inhibitor NG‐nitro‐l‐arginine methyl ester (l‐NAME) was intravenously infused and examined for its efficacy in inhibiting NOSExpand
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AMP deamination and purine exchange in human skeletal muscle during and after intense exercise
1 The present study examined the regulation of human skeletal muscle AMP deamination during intense exercise and quantified muscle accumulation and release of purines during and after intenseExpand
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Adenosine concentrations in the interstitium of resting and contracting human skeletal muscle.
BACKGROUND Adenosine has been proposed to be a locally produced regulator of blood flow in skeletal muscle. However, the fundamental questions of to what extent adenosine is formed in skeletal muscleExpand
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Intense interval training enhances human skeletal muscle oxygen uptake in the initial phase of dynamic exercise at high but not at low intensities
The present study tested the hypothesis that intense interval training enhances human skeletal muscle blood flow and oxygen uptake (V̇  O 2 ) at the onset of dynamic exercise. We also investigatedExpand
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Four weeks of speed endurance training reduces energy expenditure during exercise and maintains muscle oxidative capacity despite a reduction in training volume.
We studied the effect of an alteration from regular endurance to speed endurance training on muscle oxidative capacity, capillarization, as well as energy expenditure during submaximal exercise andExpand
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Effect of high intensity training on capillarization and presence of angiogenic factors in human skeletal muscle
The effect of intense training on endothelial proliferation, capillary growth and distribution of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF) was examined inExpand
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