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Organization of the mouse ghrelin gene and promoter: occurrence of a short noncoding first exon.
- M. Tanaka, Y. Hayashida, T. Iguchi, N. Nakao, N. Nakai, K. Nakashima
- 1 August 2001
The findings suggest that the structure of the promoter region including the short noncoding first exon and its transcriptional regulation are conserved among the mammalian ghrelin genes.
Growth hormone-independent expression of insulin-like growth factor I messenger ribonucleic acid in extrahepatic tissues of the chicken.
Results suggest that in chicken, IGF-I mRNA is expressed in liver in a GH-dependent manner after hatching, whereas in other tissues, mRNA expression is independent of GH and GHR before and after hatch, except for testis, in which GH seems to inhibit IGF- I mRNA expression.
Testis-specific and developmentally induced expression of a ghrelin gene-derived transcript that encodes a novel polypeptide in the mouse.
Expression of aberrantly spliced growth hormone receptor mRNA in the sex-linked dwarf chicken, Gifu 20.
- M. Tanaka, Y. Hayashida, M. Wakita, S. Hoshino, K. Nakashima
- BiologyGrowth regulation
- 1 December 1995
The mutation resulting in an inappropriate splicing of the GHR gene transcript is considered to be the cause of this dwarf chicken.
Thyroid hormones are involved in insulin-like growth factor-I (IGF-I) production by stimulating hepatic growth hormone receptor (GHR) gene expression in the chicken.
Two novel first exons in the prolactin receptor gene are transcribed in a tissue-specific and sexual maturation-dependent manner to encode multiple 5'-truncated transcripts in the testis of the…
Identification of a novel first exon of prolactin receptor gene expressed in the rat brain.
Results suggest that PRL-R gene expression in rat brain is controlled by the promoter for the E1(4) first exon, and putative transcription factor-binding sites, such as CCAAT, Sp1, and glucocorticoid-responsive elements, were observed at further upstream regions.
Identification of MIWI-associated Poly(A) RNAs by immunoprecipitation with an anti-MIWI monoclonal antibody.
Results strongly suggest that MIWI is involved in pachytene piRNA biogenesis and the positive regulation of target mRNA metabolism in pachedtene spermatocytes via association with pachyTene piRNAs precursors and target mRNAs.
A useful approach to total analysis of RISC-associated RNA
The method enables us to examine not only dynamic changes in miRNA and mRNA contents in RISC but also the relationship of mi RNA and target mRNA, and believes that the method can contribute to understanding cellular regulatory networks by miRNAs.
Use of transcriptional sequencing in difficult to read areas of the genome.