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Internal friction of compressed pharmaceutical powders observed in terms of the die wall pressure.
The internal friction of powders was examined during tablet preparation for lactose and phenacetin as base materials and for potassium chloride, potassium bromide and sodium chloride as model samples to find the state of the whole bed of powder was found to be plastic.
Physical characterization of erythromycin dihydrate, anhydrate and amorphous solid and their dissolution properties
Three erythromycin solids were characterized. In differential scanning calorimetry (DSC), the anhydrate exhibited only a melting endotherm at 193°C. The dihydrate was desolvated at temperatures
Coating of pharmaceutical powders by fluidized bed process. I. Aqueous enteric coating with methacrylic acid-ethylacrylate copolymer and the dissolution behavior of products.
These dissolution profiles of coated lactose particles suggested that they should be useful as a model to study oral drug delivery systems with various lag times of dissolution.