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- Publications
- Influence
HIV-inhibitory and cytotoxic oligostilbenes from the leaves of Hopea malibato.
- J. Dai, Y. Hallock, J. Cardellina, M. Boyd
- Biology, Medicine
- Journal of natural products
- 20 February 1998
Three new oligostilbenes, malibatols A (1) and B (2) and dibalanocarpol (3), together with one known oligostilbene balanocarpol (4), were isolated from the organic extract of the leaves of Hopea… Expand
Anti-HIV michellamines from Ancistrocladus korupensis.
- M. Boyd, Y. Hallock, +7 authors G. Cragg
- Chemistry, Medicine
- Journal of medicinal chemistry
- 10 June 1994
Here we report details of the isolation and determination of the absolute configurations and comparative anti-HIV activities of novel, atropisomeric naphthylisoquinoline alkaloid dimers,… Expand
Cycloviolins A-D, anti-HIV macrocyclic peptides from Leonia cymosa.
- Y. Hallock, R. Sowder, +5 authors M. Boyd
- Chemistry, Medicine
- The Journal of organic chemistry
- 14 January 2000
Four novel anti-HIV macrocyclic peptides containing 28-31 amino acid residues, named cycloviolins A-D, have been isolated from the hitherto unstudied tropical plant Leonia cymosa. Their primary… Expand
Michellamine B, a novel plant alkaloid, inhibits human immunodeficiency virus-induced cell killing by at least two distinct mechanisms.
- J. Mcmahon, M. Currens, +4 authors M. Boyd
- Biology, Medicine
- Antimicrobial agents and chemotherapy
- 1 February 1995
Studies of the mechanism of action of michellamine B, a novel anti-human immunodeficiency virus (HIV) alkaloid from the tropical plant Ancistrocladus korupensis, have revealed that the compound acts… Expand
Phytotoxins from Alternaria cassiae
- Cynthia M. Hradil, Y. Hallock, J. Clardy, D. Kenfield, G. Strobel
- Biology
- 1989
Abstract The isolation, structure determination, and phytotoxicity of stemphyperylenol, stemphyltoxin II, alterperylenol, and altertoxin I from Alternaria cassiae are reported.
Phytoactive Eremophilanes Produced by the Weed Pathogen Drechslera gigantea.
- F. Sugawara, Y. Hallock, G. Bunkers, D. Kenfield, G. Strobel, S. Yoshida
- Biology, Medicine
- Bioscience, biotechnology, and biochemistry
- 23 February 1993
Phytoactive substances were present in a culture broth of Drechslera gigantea, a pathogenic fungus of several grasses. Twelve eremophilane sesquiterpenes (1, 2, 3, 4, 6, 7, 10, 11, 12, 13, 14, and… Expand
National Cooperative Drug Discovery Groups (NCDDGs): A Successful Model for Public Private Partnerships in Cancer Drug Discovery
- Y. Hallock, G. Cragg
- Medicine
- 1 January 2003
The United States National Cancer Institute (NCI) has been investigating Nature as a source of novel agents for the treatment of cancer for over 45 years, and has contributed to the development of… Expand
Michellamines D-F, new HIV-inhibitory dimeric naphthylisoquinoline alkaloids, and korupensamine E, a new antimalarial monomer, from Ancistrocladus korupensis.
- Y. Hallock, K. Manfredi, +9 authors M. Boyd
- Chemistry, Medicine
- Journal of natural products
- 1 July 1997
New monomeric (korupensamine E, 6) and dimeric (michellamines D-F, 7-9) naphthylisoquinoline alkaloids have been isolated from exracts of the tropical liana Ancistrocladus korupensis. Structures were… Expand
Korundamine A, a novel HIV-inhibitory and antimalarial "hybrid" naphthylisoquinoline alkaloid heterodimer from Ancistrocladus korupensis.
- Y. Hallock, J. Cardellina, M. Schaeffer, G. Bringmann, G. Francois, M. Boyd
- Chemistry, Medicine
- Bioorganic & medicinal chemistry letters
- 7 July 1998
A unique heterodimeric naphthylisoquinoline alkaloid, korundamine A (2), comprised of two different monomeric biaryl halves, has been isolated from the Cameroonian tropical liana Ancistrocladus… Expand
A new discorhabdin from two sponge genera.
- M. G. Dijoux, W. R. Gamble, Y. Hallock, J. Cardellina, R. van Soest, M. Boyd
- Medicine, Biology
- Journal of natural products
- 1 April 1999