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Plant HP1 protein ADCP1 links multivalent H3K9 methylation readout to heterochromatin formation
Heterochromatin Protein 1 (HP1) recognizes histone H3 lysine 9 methylation (H3K9me) through its conserved chromodomain and maintains heterochromatin from fission yeast to mammals. However, in… Expand
Multivalent m6A motifs promote phase separation of YTHDF proteins
Dear Editor, Posttranscriptional modifications of coding and non-coding RNAs are prevalent in cells. N6-methyladenosine (mA) is the most abundant type of modification on eukaryotic messenger RNAs… Expand
SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors
Histone Modifications Regulate Chromatin Compartmentalization by Contributing to a Phase Separation Mechanism.
Eukaryotic chromosomes contain compartments of various functions, which are marked by and enriched with specific histone modifications. However, the molecular mechanisms by which these histone marks… Expand
miR‐223 Regulates Adipogenic and Osteogenic Differentiation of Mesenchymal Stem Cells Through a C/EBPs/miR‐223/FGFR2 Regulatory Feedback Loop
Several miRNAs have recently been identified to regulate adipocyte or osteoblast differentiation or both. In this study, miR‐223 was found to be involved in the reciprocal regulation of adipocyte and… Expand
Recalcitrant carbon components in glomalin-related soil protein facilitate soil organic carbon preservation in tropical forests
- J. Zhang, X. Tang, Siyuan Zhong, Guang-cai Yin, Y. Gao, X. He
- Chemistry, Medicine
- Scientific Reports
- 24 May 2017
Glomalin-related soil protein (GRSP) is known as an important microbial by-product which is crucial for preserving or accumulating soil organic carbon (SOC). However, the underlying mechanisms are… Expand
The fungal mitochondrial membrane protein, BbOhmm, antagonistically controls hypoxia tolerance.
- Zhangjiang He, X. Zhao, +7 authors Yongjun Zhang
- Biology, Medicine
- Environmental microbiology
- 1 January 2020
Adaptation to low-oxygen environment in host tissues is crucial for microbial pathogens, particuarlly fungi, to successfully infect target hosts. However, the underlying mechanisms responsible for… Expand
In-situ membrane fouling control by electrooxidation and microbial community in membrane electro-bioreactor treating aquaculture seawater.
- J. Song, Yanming Yin, Yi-han Li, Y. Gao, Y. Liu
- Chemistry, Medicine
- Bioresource technology
- 17 June 2020
Ammonia and nitrite in aquaculture recirculating seawater need to be strictly controlled to avoid deleterious effects on aquatic organisms. However, traditional biological approach can hardly meet… Expand
A fluorescent amplification strategy for high-sensitive detection of 17 β-estradiol based on EXPAR and HCR.
Environmental endocrine disruptors in the environment and food, especially 17 β-estradiol (E2), are important factors affecting the growth and development of organisms. In this research, we… Expand
Loci-specific phase separation of FET fusion oncoproteins promotes gene transcription
Abnormally formed FUS/EWS/TAF15 (FET) fusion oncoproteins are essential oncogenic drivers in many human cancers. Interestingly, at the molecular level, they also form biomolecular condensates at… Expand