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Reduced Spike-Timing Reliability Correlates with the Emergence of Fast Ripples in the Rat Epileptic Hippocampus
Ripples are sharp-wave-associated field oscillations (100-300 Hz) recorded in the hippocampus during behavioral immobility and slow-wave sleep. In epileptic rats and humans, a different and fasterExpand
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Loss of COUP-TFI Alters the Balance between Caudal Ganglionic Eminence- and Medial Ganglionic Eminence-Derived Cortical Interneurons and Results in Resistance to Epilepsy
In rodents, cortical interneurons originate from the medial ganglionic eminence (MGE) and caudal ganglionic eminence (CGE) according to precise temporal schedules. The mechanisms controlling theExpand
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Hippocampal-Dependent Spatial Memory in the Water Maze is Preserved in an Experimental Model of Temporal Lobe Epilepsy in Rats
Cognitive impairment is a major concern in temporal lobe epilepsy (TLE). While different experimental models have been used to characterize TLE-related cognitive deficits, little is known on whetherExpand
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Bases fisiopatológicas de la epilepsia del lóbulo temporal: estudios en humanos y animales
Introduccion. La epilepsia del lobulo temporal (ELT) es el tipo mas frecuente de epilepsia farmacorresistente en humanos. El tratamiento quirurgico de estos pacientes permite estudios de granExpand
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[The pathophysiological foundations of temporal-lobe epilepsy: studies in humans and animals].
INTRODUCTION Temporal lobe epilepsy (TLE) is the most frequent form of pharmaco-resistant epilepsy in human. Research using material from TLE patients undergoing surgery and animal models hasExpand
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Estudio y caracterización del modelo de status-epilepticus por litio-pilocarpina en rata
En esta tesis hemos abordado el estudio de la progresion electroclinica al status epilepticus utilizando el modelo de litio-pilocarpina en rata. Clinicamente el establecimiento del status epilepticusExpand