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Autocrine/paracrine role of adrenomedullin in cultured endothelial and mesangial cells.
- H. Michibata, M. Mukoyama, K. Nakao
- Biology, MedicineKidney international
- 1 April 1998
TLDR
Small dipeptide-based HIV protease inhibitors containing the hydroxymethylcarbonyl isostere as an ideal transition-state mimic.
- Y. Kiso, H. Matsumoto, S. Mizumoto, T. Kimura, Y. Fujiwara, K. Akaji
- Chemistry, BiologyBiopolymers
- 1999
TLDR
Disulfide Bond Formation Using the Silyl Chloride-Sulfoxide System for the Synthesis of a Cystine Peptide
- K. Akaji, T. Tatsumi, Makoto Yoshida, Tooru Kimura, Y. Fujiwara, Y. Kiso
- Chemistry, Biology
- 1 May 1992
TLDR
Synthesis of cystine-peptide by a new disulphide bond-forming reaction using the siiyl chloride–sulphoxide system
- K. Akaji, T. Tatsumi, Makoto Yoshida, Tooru Kimura, Y. Fujiwara, Y. Kiso
- Chemistry, Biology
- 1991
Methyltrichlorosilane or tetrachlorosilane in trifluoroacetic acid, in the presence of diphenylsulphoxide, is found to cleave various S-protecting groups of cysteine to form cystine directly by the…
Synthesis of porcine brain natriuretic peptide-32 using silver tetrafluoroborate as a new deprotecting reagent of the S-trimethylacetamidomethyl group.
- M. Yoshida, K. Akaji, Y. Kiso
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 25 January 1990
TLDR
Racemization-free synthesis of C-terminal cysteine-peptide using 2-chlorotrityl resin.
- Y. Fujiwara, K. Akaji, Y. Kiso
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 15 March 1994
TLDR
Solution-phase synthesis of porcine brain natriuretic peptide (pBNP) using S-trimethylacetamidomethylcysteine.
- Y. Kiso, M. Yoshida, T. Kimura, Y. Fujiwara, M. Shimokura, K. Akaji
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 25 May 1990
The hexadodecapeptide corresponding to the entire amino acid sequence of porcine brain natriuretic peptide (pBNP) was synthesized by assembling four segments in solution, followed by HF deprotection…
Deprotection of the S-trimethylacetamidomethyl (Tacm) group using silver tetrafluoroborate: application to the synthesis of porcine brain natriuretic peptide-32 (pBNP-32).
- M. Yoshida, T. Tatsumi, Y. Kiso
- Chemistry, BiologyChemical & pharmaceutical bulletin
- 25 June 1990
TLDR
Anchoring of Fmoc amino acid to 4-alkoxybenzyl alcohol resin using a new esterification reagent
- K. Akaji, N. Kuriyama, Tooru Kimura, Y. Fujiwara, Y. Kiso
- Chemistry
- 26 May 1992
Fluoren-9-ylmethyloxycarbonyl (Fmoc) amino acid chloride as an efficient reagent for anchoring Fmoc amino acid to 4-alkoxybenzyl alcohol resin.
- K. Akaji, Hideo Tanaka, Y. Kiso
- Chemistry
- 25 December 1990
Esterification of Fmoc amino acids to 4-alkoxybenzyl alcohol polystyrene through acid chlorides was achieved in high yield with practically no racemization. This reaction is especially effective for…
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