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MiR‐185‐5p suppresses HBV gene expression by targeting ELK1 in hepatoma carcinoma cells
It is found that miR‐185‐5p decreases HBV S1p activity by targeting ELK1, which may provide a promising therapeutic strategy for HBV infection. Expand
LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells
The in vivo experiments showed that the inhibitory effect of curcumin on the growth of cisplatin-resistant CRC cells was reserved by the ectopic expression of KCNQ1OT1, and Administration ofCurcumin could effectively downregulate KCNNQ 1OT1 expression, thus reversing cis platin resistance in CRC cells. Expand
Hepatitis B Virus DNA Polymerase Restrains Viral Replication Through the CREB1/HOXA Distal Transcript Antisense RNA Homeobox A13 Axis
Long noncoding RNAs (lncRNAs) have been associated with infection and hepatitis B virus (HBV)‐related diseases, though the underlying mechanisms remain unclear.
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
MT1JP alleviated proliferation, migration and invasion, and induced apoptosis in cholangiocarcinoma cells by regulating miR-18a-5p/FBP1 axis. Expand
HBV DNA polymerase restrains viral replication via the CREB1-HOTTIP-HOXA13 axis.
It is demonstrated that HBV DNA pol attenuates HBV replication via activation of the CREB1-HOTTIP-HOXA13 axis, shed light on the mechanism by which HBV restrains replication to contribute to persistent infection. Expand
FOXK1 plays an oncogenic role in the progression of hilar cholangiocarcinoma
Results indicated that FOXK1 plays an oncogenic role in HC progression and can serve as a novel therapeutic target for HC. Expand