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MiR‐185‐5p suppresses HBV gene expression by targeting ELK1 in hepatoma carcinoma cells
- Hong-xia Fan, Y. Feng, Xiaopei Zhao, Yu-Ze He, Hua Tang
- Biology, Medicine
- Life sciences
- 15 November 2018
It is found that miR‐185‐5p decreases HBV S1p activity by targeting ELK1, which may provide a promising therapeutic strategy for HBV infection. Expand
LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells
- Zhi-hai Zheng, H. You, Y. Feng, Zhong-Tao Zhang
- Medicine, Chemistry
- Molecular and Cellular Biochemistry
- 5 August 2020
The in vivo experiments showed that the inhibitory effect of curcumin on the growth of cisplatin-resistant CRC cells was reserved by the ectopic expression of KCNQ1OT1, and Administration ofCurcumin could effectively downregulate KCNNQ 1OT1 expression, thus reversing cis platin resistance in CRC cells. Expand
Hepatitis B Virus DNA Polymerase Restrains Viral Replication Through the CREB1/HOXA Distal Transcript Antisense RNA Homeobox A13 Axis
Long noncoding RNAs (lncRNAs) have been associated with infection and hepatitis B virus (HBV)‐related diseases, though the underlying mechanisms remain unclear.
LncRNA MT1JP plays a protective role in intrahepatic cholangiocarcinoma by regulating miR-18a-5p/FBP1 axis
- Wei Zhao, Jing Zhao, Xiao Guo, Y. Feng, Bingyuan Zhang, Lantian Tian
- BMC cancer
- 8 February 2021
MT1JP alleviated proliferation, migration and invasion, and induced apoptosis in cholangiocarcinoma cells by regulating miR-18a-5p/FBP1 axis. Expand
HBV DNA polymerase restrains viral replication via the CREB1-HOTTIP-HOXA13 axis.
It is demonstrated that HBV DNA pol attenuates HBV replication via activation of the CREB1-HOTTIP-HOXA13 axis, shed light on the mechanism by which HBV restrains replication to contribute to persistent infection. Expand
FOXK1 plays an oncogenic role in the progression of hilar cholangiocarcinoma
- Y. Feng, Z. Bai, Jianning Song, Zhongtao Zhang
- Medicine, Biology
- Molecular medicine reports
- 25 November 2020
Results indicated that FOXK1 plays an oncogenic role in HC progression and can serve as a novel therapeutic target for HC. Expand
Chitosan: Drug Release and Bone Tissue Engineering
Corrigendum to "LncRNA n335586/miR-924/CKMT1A axis contributes to cell migration and invasion in hepatocellular carcinoma cells" [Canc. Lett. 429 (2018) 89-99].