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- Publications
- Influence
Total syntheses and initial evaluation of [Ψ[C(═S)NH]Tpg⁴]vancomycin, [Ψ[C(═NH)NH]Tpg⁴]vancomycin, [Ψ[CH₂NH]Tpg⁴]vancomycin, and their (4-chlorobiphenyl)methyl derivatives: synergistic binding pocket…
- Akinori Okano, A. Nakayama, +5 authors D. Boger
- Chemistry, Medicine
- Journal of the American Chemical Society
- 9 March 2015
Full details of studies are disclosed on the total syntheses of binding pocket analogues of vancomycin bearing the peripheral L-vancosaminyl-1,2-D-glucosyl disaccharide that contain changes to a key… Expand
Effect of Salvia miltiorrhiza Bunge injection on anticardiolipin antibody production induced by beta2 glycoprotein.
AIM
To explore the therapeutic effect and the mechanism of Chinese herbs on antiphospholipid syndrome (APS) by observing the effect of Salvia miltiorrhiza Bunge injectio (SmBI) on anticardiolipin… Expand
Total synthesis of celogentin C by stereoselective C-H activation.
the most potent isolate (IC50= 0.8 mm ; IC= inhibitory concentration) from the celogentin/moroidin family, whose members possess inhibitory activity against tubulin polymerization. Its highly unusual… Expand
Facile benzo-ring construction via palladium-catalyzed functionalization of unactivated sp3 C-H bonds under mild reaction conditions.
- Y. Feng, Y. Wang, Bradley J. Landgraf, S. Liu, G. Chen
- Chemistry, Medicine
- Organic letters
- 28 June 2010
A practical synthetic method for the annulation of benzo-rings by the intramolecular coupling of an aryl iodide and a methylene C-H bond is described. The palladium-catalyzed C-H functionalization is… Expand
Enzymatic Glycosylation of Vancomycin Aglycon: Completion of a Total Synthesis of Vancomycin and N- and C-Terminus Substituent Effects of the Aglycon Substrate
- A. Nakayama, Akinori Okano, +4 authors D. Boger
- Chemistry, Medicine
- Organic letters
- 23 June 2014
Studies on the further development of the sequential glycosylations of the vancomycin aglycon catalyzed by the glycosyltransferases GtfE and GtfD and the observation of unusual, perhaps unexpected,… Expand
Total syntheses of the monoterpene indole alkaloids (±)-alstilobanine A and E and (±)-angustilodine.
- Y. Feng, M. M. Majireck, S. Weinreb
- Chemistry, Medicine
- The Journal of organic chemistry
- 3 January 2014
A synthetic strategy has been developed culminating in stereoselective total syntheses of the small class of unusual monoterpenoid indole alkaloids exemplified by alstilobanines A (3) and E (2) and… Expand
An efficient construction of quinazolin-4(3H)-ones under microwave irradiation
The highly accelerated Niementowski synthesis of quinazolin-4(3H)-one and quinazolin-2,4- dione derivatives under microwave irradiation is reported. Compared to the conventional conditions, this new… Expand
Visible-Light-Driven Photocatalytic Initiation of Radical Thiol-Ene Reactions Using Bismuth Oxide.
- O. Fadeyi, J. Mousseau, +5 authors R. Robinson
- Chemistry, Medicine
- Organic letters
- 17 November 2015
A nontoxic and inexpensive photocatalytic initiation of anti-Markovnikov hydrothiolation of olefins using visible light is reported. This method is characterized by low catalyst loading, thereby… Expand
Total synthesis of the unusual monoterpenoid indole alkaloid (±)-alstilobanine A.
- Y. Feng, M. M. Majireck, S. Weinreb
- Chemistry, Medicine
- Angewandte Chemie
- 14 December 2012
The monoterpene indole alkaloids, which are usually comprised of a tryptamine moiety appended to a single C9- or C10-terpenoid unit, constitute one of the largest known classes of natural… Expand