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Hippo Pathway-independent Restriction of TAZ and YAP by Angiomotin*
The Hippo pathway restricts the activity of transcriptional co-activators TAZ and YAP by phosphorylating them for cytoplasmic sequestration or degradation. In this report, we describe an independentExpand
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TEADs Mediate Nuclear Retention of TAZ to Promote Oncogenic Transformation*
The transcriptional coactivators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. The expression level of TAZ is recently shown to be elevated in invasive breastExpand
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WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
The transcriptional co-activators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. YAP and TAZ both possess WW domains, which are important protein–proteinExpand
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The hippo pathway in biological control and cancer development
The Hippo pathway is an evolutionally conserved protein kinase cascade involved in regulating organ size in vivo and cell contact inhibition in vitro by governing cell proliferation and apoptosis.Expand
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Abstract LB-17: WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ
The transcriptional co-activators YAP and TAZ are downstream targets inhibited by the Hippo tumor suppressor pathway. YAP and TAZ both possess WW domains which are important protein-proteinExpand
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