• Publications
  • Influence
Detection and localization of single molecular recognition events using atomic force microscopy
Because of its piconewton force sensitivity and nanometer positional accuracy, the atomic force microscope (AFM) has emerged as a powerful tool for exploring the forces and the dynamics of theExpand
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Nanoscale mapping of the elasticity of microbial cells by atomic force microscopy
Single microbial cells can show important local variations of elasticity due to the complex, anisotropic composition of their walls. An example of this is the yeast during cell division, where chitinExpand
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Force probing surfaces of living cells to molecular resolution.
Biological processes rely on molecular interactions that can be directly measured using force spectroscopy techniques. Here we review how atomic force microscopy can be applied to force probeExpand
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Scanning probe microscopy.
During the past year, scanning probe microscopy, especially atomic force microscopy (AFM), has taken root in the biological sciences community, as is evident from the large number of publications andExpand
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Identification of a Gene Cluster for the Biosynthesis of a Long, Galactose-Rich Exopolysaccharide in Lactobacillus rhamnosus GG and Functional Analysis of the Priming Glycosyltransferase
ABSTRACT Cell surface polysaccharides have an established role as virulence factors in human bacterial pathogens. Less documented are the biosynthesis and biological functions of surfaceExpand
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Cell Surface of Lactococcus lactis Is Covered by a Protective Polysaccharide Pellicle*
In Gram-positive bacteria, the functional role of surface polysaccharides (PS) that are not of capsular nature remains poorly understood. Here, we report the presence of a novel cell wall PS pellicleExpand
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Atomic force microscopy, a powerful tool in microbiology.
  • Y. Dufrêne
  • Biology, Medicine
  • Journal of bacteriology
  • 1 October 2002
Understanding the functions of microbial cell surfaces requires knowledge of their structural and physical properties. Electron microscopy has long been recognized as a key technique in microbiologyExpand
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Towards nanomicrobiology using atomic force microscopy
  • Y. Dufrêne
  • Biology, Medicine
  • Nature Reviews Microbiology
  • 1 September 2008
At the cross-roads of nanoscience and microbiology, the nanoscale analysis of microbial cells using atomic force microscopy (AFM) is an exciting, rapidly evolving research field. Over the pastExpand
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Force-induced formation and propagation of adhesion nanodomains in living fungal cells
Understanding how cell adhesion proteins form adhesion domains is a key challenge in cell biology. Here, we use single-molecule atomic force microscopy (AFM) to demonstrate the force-inducedExpand
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Application of X-ray photoelectron spectroscopy to microorganisms
The use of X-ray photoelectron spectroscopy (XPS) for the analysis of microbial cell surfaces is described and discussed. This technique is well established in materials science; however, itsExpand
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