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Tumor and serum gamma-glutamyl transpeptidase, new prognostic and molecular interpretation of an old biomarker in gastric cancer
Background Gastric Cancer is one of the most lethal malignancies worldwide. Gamma-glutamyl transpeptidase (GGT) is an enzyme mainly involved in cellular glutathione homeostasis. We aim to explore the… Expand
Human papillomavirus and oral squamous cell carcinoma: A review of HPV-positive oral squamous cell carcinoma and possible strategies for future.
Oral squamous cell carcinoma (OSCC) is a common cancer worldwide. Besides tobacco use and alcohol consumption, human papillomavirus (HPV) infection has also been identified as a risk factor for OSCC… Expand
Chromium supplementation for adjuvant treatment of type 2 diabetes mellitus: Results from a pooled analysis
- Haohai Huang, Guangzhao Chen, Y. Dong, Yongkun Zhu, Honglang Chen
- Molecular nutrition & food research
SCOPE We conducted a pooled analysis of randomized controlled trials to evaluate the effects of chromium supplementation on clinically relevant metabolic biomarkers in type 2 diabetes mellitus (T2DM)… Expand
Inflammatory breast cancer outcomes by breast cancer subtype: a population-based study.
AIM To assess the outcomes of breast cancer subtype in inflammatory breast cancer (IBC). METHODS We retrospectively assessed IBC patients from the SEER program. RESULTS We identified 626… Expand
Suppressor of Ty homolog-5, a novel tumor-specific human telomerase reverse transcriptase promoter-binding protein and activator in colon cancer cells
The human telomerase reverse transcriptase (hTERT) promoter promotes differential hTERT gene expression in tumor cells and normal cells. However, information on the mechanisms underlying the… Expand
The 21-gene recurrence score and effects of adjuvant radiotherapy after breast conserving surgery in early-stage breast cancer.
Aim: To investigate the associations with the 21-gene recurrence score (RS) and effect of adjuvant radiotherapy (RT) for early-stage breast cancer after breast conserving surgery. Methods: We… Expand
21-Gene Recurrence Score Assay and Outcomes of Adjuvant Radiotherapy in Elderly Women With Early-Stage Breast Cancer After Breast-Conserving Surgery
Introduction: To assess the role of the 21-gene recurrence score (RS) assay on decision-making of postoperative radiotherapy (RT) following breast-conserving surgery (BCS) in elderly women with… Expand
Relationship of metformin with the risk of pancreatic cancer in patients with type 2 diabetes: a meta-analysis
Aims: This study is to systematically investigate the relationship between metformin and risk of pancreatic cancer in patients with type 2 diabetes mellitus. Methods: A systematic literature search… Expand
Effect of quercetin supplementation on plasma lipid profiles, blood pressure, and glucose levels: a systematic review and meta-analysis.
CONTEXT Clinical trials examining the cardiovascular protective effects of quercetin in humans have reported conflicting results. OBJECTIVE The aim of this systematic review was to summarize… Expand
The Distribution and Outcomes of the 21-Gene Recurrence Score in T1-T2N0 Estrogen Receptor-Positive Breast Cancer With Different Histologic Subtypes
- J. Wang, Z. He, Y. Dong, Jiayuan Sun, Wen-wen Zhang, San-Gang Wu
- Front. Genet.
- 17 December 2018
Background: The clinical value of 21-gene recurrence score (RS) in various breast cancer histologic subtypes is not well established. Aims: To assess the distribution and outcomes of the 21-gene RS… Expand