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Foxo3 circular RNA promotes cardiac senescence by modulating multiple factors associated with stress and senescence responses
Aims Circular RNAs are a subclass of non-coding RNAs detected within mammalian cells. This study was designed to test the roles of a circular RNA circ-Foxo3 in senescence using in vitro and in vivoExpand
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Intracoronary infusion of Wharton’s jelly-derived mesenchymal stem cells in acute myocardial infarction: double-blind, randomized controlled trial
BackgroundThe use of adult stem cells is limited by the quality and quantity of host stem cells. It has been demonstrated that Wharton’s jelly–derived mesenchymal stem cells (WJMSCs), a primitiveExpand
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Effect of Taurine-Conjugated Ursodeoxycholic Acid on Endoplasmic Reticulum Stress and Apoptosis Induced by Advanced Glycation End Products in Cultured Mouse Podocytes
BACKGROUND Activations of death receptors and mitochondrial damage are well-described common apoptotic pathways. Recently, a novel pathway via endoplasmic reticulum (ER) stress has been reported. Expand
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Subsidence of Titanium Mesh Cage: A Study Based on 300 Cases
Study Design A cohort study. Objective To clarify the risk factors for the subsidence of the titanium mesh cage (TMC) after anterior cervical corpectomy and fusion, and to discuss their clinicalExpand
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Purinergic Signaling: A Fundamental Mechanism in Neutrophil Activation
Neutrophil activation by infectious and inflammatory signals requires ATP release and its feedback through purinergic receptors. Feedback for Function Neutrophils migrate to sites of infection, whereExpand
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Diagnosis and treatment of community‐acquired pneumonia in adults: 2016 clinical practice guidelines by the Chinese Thoracic Society, Chinese Medical Association
Community‐acquired pneumonia (CAP) in adults is an infectious disease with high morbidity in China and the rest of the world. With the changing pattern in the etiological profile of CAP and advancesExpand
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Surgical Strategy for Multilevel Severe Ossification of Posterior Longitudinal Ligament in the Cervical Spine
Study Design A retrospective clinical study was conducted. Objective To compare surgical outcome of anterior approach (corpectomy and fusion) with that of posterior approach (laminoplasty orExpand
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miR-122 targets NOD2 to decrease intestinal epithelial cell injury in Crohn's disease.
Crohn's disease (CD) is one of the two major types of inflammatory bowel disease (IBD) thought to be caused by genetic and environmental factors. Recently, miR-122 was found to be deregulated inExpand
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Vitamin D deficiency promotes nonalcoholic steatohepatitis through impaired enterohepatic circulation in animal model.
  • M. Kong, L. Zhu, +7 authors Z. Duan
  • Biology, Medicine
  • American journal of physiology. Gastrointestinal…
  • 1 November 2014
Vitamin D deficiency (VDD) or insufficiency is recognized for its association with nonalcoholic steatohepatitis (NASH), whereas the underlying mechanism remains unknown. Using animal models, we foundExpand
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Types of Organ Involvement in Patients with Immunoglobulin G4-related Disease
Background:Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized systemic disease that can involve multiple organs and various clinical phenotypes. The purpose of this study was toExpand
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