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SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence
TLDR
We have developed a web-based software, SVMProt, for SVM classification of a protein into functional family from its primary sequence. Expand
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TTD: Therapeutic Target Database
TLDR
We introduce a Therapeutic Target Database (TTD), which contains information about the known therapeutic protein and nucleic acid targets together with the targeted disease conditions, the pathway information and the corresponding drugs/ligands directed at each of these targets. Expand
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PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence
TLDR
We introduce PROFEAT (Protein Features) is a web server for computing commonly-used structural and physicochemical features of proteins and peptides from amino acid sequence. Expand
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Thermal evaluation of vertical greenery systems for building walls
This research involves the study of 8 different vertical greenery systems (VGSs) installed in HortPark to evaluate the thermal impacts on the performance of buildings and their immediate environmentExpand
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Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics
TLDR
We describe an update of the Therapeutic target database (TTD) previously featured in NAR. Expand
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Update of TTD: Therapeutic Target Database
TLDR
We updated TTD by significantly expanding the target data to include 348 successful, 292 Clinical trial and 1254 research targets, and added drug data for 1514 approved, 1212 clinical trial and 2302 experimental drugs linked to their primary targets. Expand
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Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes
Rab10 activation promotes GLUT4 storage vesicle recruitment to the plasma membrane in response to insulin and coordinates with myosin-Va to mediate vesicle fusion.
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miR-200b inhibits TGF-β1-induced epithelial-mesenchymal transition and promotes growth of intestinal epithelial cells
Inflammatory bowel disease (IBD), which consists of Crohn's disease (CD) and ulcerative colitis (UC), is a chronic, inflammatory disorder of the gastro-intestinal tract with unknown etiology. CurrentExpand
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Therapeutic Targets: Progress of Their Exploration and Investigation of Their Characteristics
Modern drug discovery is primarily based on the search and subsequent testing of drug candidates acting on a preselected therapeutic target. Progress in genomics, protein structure, proteomics, andExpand
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Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
TLDR
We describe an update of the Therapeutic Target Database (TTD) previously featured in NAR. Expand
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