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[Prognostic analysis of acute-on-chronic liver failure after withdrawal of nucleos(t)ide analogues for antiviral treatment of chronic hepatitis B].
TLDR
MELD score and hepatic encephalopathy are closely associated with the prognosis of patients with ACLF after withdrawal of NAs for the antiviral treatment of chronic hepatitis B.
Epac-PKCalpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammation.
TLDR
The participation of PKCα in Epac signaling in P2X3R-mediated hyperalgesia is studied, confirming the involvement of Epacs and suggesting that PKC α also plays an essential role in producing complex inflammation-induced receptor-mediatedHyperalgesic responses.
Bacillus cereus HS24 Suppresses Conidia Germination of Magnaporthe oryzae by Inhibiting the Ca2+ Signaling Pathway
TLDR
The results showed that conidial germination of M. oryzae was significantly inhibited by HS24 suspension, and the inhibition rate reached to 97.83% at the concentration of 10 CFU/ml, and HS24 may inhibit conidia germination and germ tube elongation through inhibiting the Ca2+ signaling pathway.
Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region
TLDR
Hsp90 inhibitor induces nuclear translocation of HSF1 predominantly in hippocampal CA1 region and results in down-regulation of Hsp90 activity in hippocampus.