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Synthesis and Potent Antifolate Activity and Cytotoxicity of B-Ring Deaza Analogues of the Nonpolyglutamatable Dihydrofolate Reductase Inhibitor
Six new B-ring analogues of the nonpolyglutamatable antifolate Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithine (PT523, 3) were synthesized with a view to determining the effect ofExpand
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A Scenario-Based Service-Oriented Rapid Multi-Agent Distributed Modeling and Simulation Framework for SoS/SOA and Its Applications
The paper presents a scenario-driven multi-agent framework for rapid simulation generation and verification. Expand
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A scheduling system for exploiting data and task parallelism on PC laboratory clusters
Presents a framework for deciding on a good execution strategy for a given program based on the available data and task parallelism in the program, and demonstrates the feasibility of automatic cluster assignment, processor set selection and data partition functions. Expand