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Normalization of urinary drug concentrations with specific gravity and creatinine.
TLDR
Drug/metabolite concentration normalization by these procedures is recommended for urine testing programs, especially as a means of coping with dilute specimens.
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Urine drug testing of chronic pain patients: licit and illicit drug patterns.
TLDR
Being the first study of this type, these data present a large array of information on licit and illicit drug use, drug detection frequencies, drug/metabolite patterns, and multi-drug use combinations in pain patients.
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A comprehensive study of the stability of cocaine and its metabolites.
TLDR
The incubation of COC in enzyme solutions provided further evidence of the generally accepted hypothesis that COC is hydrolyzed to EME by PChE and to BE by chemical hydrolysis.
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Alternative specimens for workplace drug testing.
TLDR
The present focus is on oral fluid (saliva), hair, and sweat, which will become routine in all areas of forensic toxicology in future years.
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Disposition of heroin and its metabolites in heroin-related deaths.
TLDR
The identification of heroin and 6-acetylmorphine in biological tissues effectively established the presence of heroin in cases of acute narcotic intoxication.
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Oral fluid drug testing of chronic pain patients. I. Positive prevalence rates of licit and illicit drugs.
TLDR
The pattern of licit and illicit drugs and metabolites observed in oral fluid paralleled results reported earlier for urine, indicating that oral fluid is a viable option for use in compliance monitoring programs of chronic pain patients.
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Garriott's Medicolegal Aspects of Alcohol
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Concentration of cocaine and metabolites in plasma of humans following intravenous administration and smoking of cocaine.
TLDR
Plasma obtained from 10 human subjects at various intervals after administration of two rapid doses of cocaine, either intravenously or by smoking, and multiple doses by smoking and intravenously confirmed that BE is the principle metabolite of COC in blood.
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Oxycodone involvement in drug abuse deaths: a DAWN-based classification scheme applied to an oxycodone postmortem database containing over 1000 cases.
TLDR
An oxycodone postmortem database was created from 1243 solicited cases from Medical Examiner and Coroner offices in 23 states in the United States over the period from August 27, 1999, through January 17, 2002, and indicated a general recognition of the role of abuse of multiple drugs in causing fatalities.
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Opiate analysis in cadaveric blowfly larvae as an indicator of narcotic intoxication.
TLDR
Analysis of larvae and liver for opiates (morphine) was conducted by radioimmunoassay and good qualitative and quantitative correlation was observed in both the positive and negative groups.
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