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Th1/Th2 cytokine expression in diabetic retinopathy.
Diabetic retinopathy (DR), an important complication of diabetes mellitus (DM), is not well understood. T helper cell balance (Th1/Th2) is involved in various autoimmune diseases; however, its role… Expand
Bioinformatics-based design of novel antigenic B-cell linear epitopes of Deinagkistrodon acutus venom.
- Y. Cao, G-N Guo, +4 authors M-H Liu
- Biology, Medicine
- European review for medical and pharmacological…
OBJECTIVE With the help of bioinformatics analysis, we wished to develop a novel antivenom against the Deinagkistrodon (D.) acutus snake venom using B-cell linear epitopes of three primary toxins… Expand
MiR-7 regulates the PI3K/AKT/VEGF pathway of retinal capillary endothelial cell and retinal pericytes in diabetic rat model through IRS-1 and inhibits cell proliferation.
OBJECTIVE To investigate the role of miR-7 in diabetic retinopathy and the underlying mechanism. MATERIALS AND METHODS The rat model of diabetic retinopathy (DR) was established. After that, the… Expand