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Empirical and deterministic accuracies of across-population genomic prediction
BackgroundDifferences in linkage disequilibrium and in allele substitution effects of QTL (quantitative trait loci) may hinder genomic prediction across populations. Our objective was to develop aExpand
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Impact of QTL properties on the accuracy of multi-breed genomic prediction
BackgroundAlthough simulation studies show that combining multiple breeds in one reference population increases accuracy of genomic prediction, this is not always confirmed in empirical studies. ThisExpand
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Validation of genomic predictions for body weight in broilers using crossbred information and considering breed-of-origin of alleles
BackgroundPig and poultry breeding programs aim at improving crossbred (CB) performance. Selection response may be suboptimal if only purebred (PB) performance is used to compute genomic estimatedExpand
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Optimizing genomic reference populations to improve crossbred performance
Background In pig and poultry breeding, the objective is to improve the performance of crossbred production animals, while selection takes place in the purebred parent lines. One way to achieve thisExpand
Inbreeding depression across the genome of Dutch Holstein Friesian dairy cattle
Background Inbreeding depression refers to the decrease in mean performance due to inbreeding. Inbreeding depression is caused by an increase in homozygosity and reduced expression of (on average)Expand
Optimizing design to estimate genetic correlations between environments with common environmental effects
Abstract Breeding programs for different species aim to improve performance by testing members of full-sib (FS) and half-sib (HS) families in different environments. When genotypes respondExpand