• Publications
  • Influence
The precancer risk of betel quid chewing, tobacco use and alcohol consumption in oral leukoplakia and oral submucous fibrosis in southern Taiwan
In areas where the practise of betel quid chewing is widespread and the chewers also often smoke and drink alcohol, the relation between oral precancerous lesion and condition to the three habits isExpand
  • 233
  • 8
  • PDF
Varying Effects of Corneal Thickness on Intraocular Pressure Measurements with Different Tonometers
AbstractAimsTo compare the intraocular pressure (IOP) measurements using the Goldmann applanation tonometer (GAT), noncontact tonometer (NCT), and ocular blood flow tonometer (OBFT), and to evaluateExpand
  • 107
  • 5
Peri-ictal Normalization of Visual Cortex Excitability in Migraine: an MEG Study
To delineate if the change in cortical excitability persists across migraine attacks, visual evoked magnetic fields (VEF) were measured in patients with migraine without aura during the interictal (nExpand
  • 45
  • 5
  • PDF
Gene–gene synergistic effect on atopic asthma: tumour necrosis factor‐α‐308 and lymphotoxin‐α‐NcoI in Taiwan's children
Background Asthma is now known to be an inflammatory response caused by the release of inflammatory mediators and cytokines. Tumour necrosis factor (TNF) is a potent cytokine in the inflammationExpand
  • 53
  • 4
Association of interferon‐γ and interferon regulatory factor 1 polymorphisms with asthma in a family‐based association study in Taiwan
  • T. Wang, Y-T Chu, +4 authors Y.-C. Ko
  • Medicine
  • Clinical and experimental allergy : journal of…
  • 1 September 2006
Background Asthma is a multi‐factorial disorder caused by complex interactions between genetic and environmental factors. IFN‐γ and IFN regulatory factor 1 (IRF‐1) affect Th1/Th2 cytokine balance,Expand
  • 21
  • 2
The polymorphism -863C/A in tumour necrosis factor-alpha gene contributes an independent association to gout.
OBJECTIVE To investigate the associations between polymorphisms in the promoter of the tumour necrosis factor-alpha (TNF-alpha) gene and gout. METHODS The polymorphisms -308G/A and -863C/A in theExpand
  • 24
  • 2
  • PDF
Molecular analysis of thiopurine S‐methyltransferase alleles in Taiwan aborigines and Taiwanese
  • H. Lu, M. Shih, +4 authors J-G Chang
  • Biology, Medicine
  • Journal of clinical pharmacy and therapeutics
  • 1 February 2006
Background:  Thiopurine S‐methyltransferase (TPMT) is a cytosolic enzyme involved in the metabolism of these thiopurine drugs. Methylation of thiopurine drugs by TPMT competes with the formation ofExpand
  • 14
  • 2
Cancer aggregation and complex segregation analysis of families with female non-smoking lung cancer probands in Taiwan.
Previous studies have found that having a first-degree blood relative with lung cancer was a possible predictor of lung cancer risk, but some studies have indicated that the association isExpand
  • 46
  • 1
The cyclic GMP-dependent protein kinase II gene associates with gout disease: identified by genome-wide analysis and case–control study
Objective: To identify the position of a gout susceptibility gene. Methods: A genome-wide scan was performed using 382 random polymorphic microsatellite markers spread across 22 autosomes in aExpand
  • 18
  • 1
Effect of latanoprost 0.005% and brimonidine tartrate 0.2% on pulsatile ocular blood flow in normal tension glaucoma
Aim: To determine the effect of brimonidine tartrate 0.2% and latanoprost 0.005% on pulsatile ocular blood flow (POBF) in patients with normal tension glaucoma (NTG). Method: NTG patients withExpand
  • 40
  • PDF