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Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease
TLDR
Levodopa helps in reducing the frequency and duration of ‘off’‐related FOG and distinction amongst FOG subtypes enables evaluation of distinctive therapeutic response. Expand
Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa
TLDR
Stride-to-stride variability is especially impaired among PD subjects with a history of falls, suggesting, for the first time, the possibility of exaggerated impairment of internal clock function in PD fallers. Expand
Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait
TLDR
It is found that the ability to regulate the stride-to-stride variations in gait timing and maintain a stable walking rhythm is markedly impaired in subjects with freezing of gait, and the inability to control cadence might play an important role in this debilitating phenomenon. Expand
Is freezing of gait in Parkinson's disease related to asymmetric motor function?
TLDR
The results of this study suggest that bilateral uncoordinated gait and marked gait asymmetry, but not asymmetry in motor performance in general, are associated with FOG. Expand
Falls in outpatients with Parkinson's disease: frequency, impact and identifying factors.
TLDR
It is confirmed that falls are a common problem among patients with advanced PD and suggest easily measurable features that may be used to prospectively identify those PD patients with the greatest risk of falls. Expand
Relationship between freezing of gait (FOG) and other features of Parkinson’s: FOG is not correlated with bradykinesia
TLDR
Levodopa decreases FOG in PD, apparently an independent motor symptom, caused by a paroxysmal pathology that is different from that responsible for bradykinesia, rigidity or postural instability. Expand
Subjective memory complaints in elders: depression, anxiety, or cognitive decline?
TLDR
To study the association of subjective memory complaints (SMC) with affective state and cognitive performance in elders, a large number of elders were surveyed and it was found that the number of complaints was higher in elders with a negative affect than in those with a positive one. Expand
Striatal dopa and glucose metabolism in PD patients with freezing of gait
TLDR
In freezing PD, caudate uptake of FDG and FDOPA was reduced, whereas putamen FDOPA decrease was associated with FDG increase, and Right hemisphere circuitry seemed to be more affected in freezing patients. Expand
Cognition in multiple system atrophy: neuropsychological profile and interaction with mood
TLDR
The results showed that cognitive and mood characteristics could distinguish M SA-P from MSA-C and that anxiety and depression are related to cognitive decline, and that neuropsychological assessments of MSA patients should test for and then take into account their level of anxiety and Depression. Expand
Efficacy of pharmacological treatment of dystonia: evidence‐based review including meta‐analysis of the effect of botulinum toxin and other cure options
TLDR
A literature review based on MEDLINE and the Cochrane Library and manual search of the most important journals was performed to identify the relevant publications issued between 1973 and 2003 concluded that botulinum toxin has obvious benefit and trihexyphenidyl in high dosages is effective for the treatment of segmental and generalized dystonia in young patients. Expand
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