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- Influence
The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: comparative effectiveness of a time-varying treatment with competing risks.
- J. Holcomb, D. D. del Junco, +15 authors M. Rahbar
- Medicine
- JAMA surgery
- 1 February 2013
OBJECTIVE
To relate in-hospital mortality to early transfusion of plasma and/or platelets and to time-varying plasma:red blood cell (RBC) and platelet:RBC ratios.
DESIGN
Prospective cohort study… Expand
Prehospital Transfusion of Plasma and Red Blood Cells in Trauma Patients
- J. Holcomb, Daryn P. Donathan, +11 authors C. Wade
- Medicine
- Prehospital emergency care : official journal of…
- 2 January 2015
Abstract Objective. Earlier use of plasma and red blood cells (RBCs) has been associated with improved survival in trauma patients with substantial hemorrhage. We hypothesized that prehospital… Expand
C9orf72 ablation causes immune dysregulation characterized by leukocyte expansion, autoantibody production, and glomerulonephropathy in mice
- A. Atanasio, Vilma Decman, +24 authors Ka-man V Lai
- Biology, Medicine
- Scientific reports
- 16 March 2016
The expansion of a hexanucleotide (GGGGCC) repeat in C9ORF72 is the most common cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Both the function of C9ORF72 and the… Expand
A Neonatal Fc Receptor-Targeted Mucosal Vaccine Strategy Effectively Induces HIV-1 Antigen-Specific Immunity to Genital Infection
- L. Lu, Senthilkumar Palaniyandi, +6 authors Xiaoping Zhu
- Biology, Medicine
- Journal of Virology
- 17 August 2011
ABSTRACT Strategies to prevent the sexual transmission of HIV include vaccines that elicit durable, protective mucosal immune responses. A key to effective mucosal immunity is the capacity for… Expand
Severe Acute Pancreatitis in China: Etiology and Mortality on 1976 Patients
- Y. Bai, Y. Liu, +14 authors Zhaoshen Li
- Medicine
- Pancreas
- 1 October 2007
Objectives: Many epidemiological studies have recently been published on acute pancreatitis; however, there is no known published report on pancreatitis in China. The present study aims to assess the… Expand
Cluster-Based Consensus Time Synchronization for Wireless Sensor Networks
- J. Wu, L. Zhang, Y. Bai, Yunshan Sun
- Computer Science
- IEEE Sensors Journal
- 1 March 2015
TLDR
Prophylactic Antibiotics Cannot Reduce Infected Pancreatic Necrosis and Mortality in Acute Necrotizing Pancreatitis: Evidence From a Meta-Analysis of Randomized Controlled Trials
BACKGROUND:There is no agreement whether intravenous prophylactic antibiotics can reduce infected pancreatic necrosis and mortality in acute necrotizing pancreatitis (ANP). We performed a… Expand
Analytical methods in lipidomics and their applications.
■ CONTENTS Analytical Methods of Lipidomics 162 Extraction Methods of Lipids 163 Direct-Infusion MS-Based Lipidomics Analysis 163 Electrospray Ionization (ESI) MS 163 Matrix-Assisted Laser Desorption… Expand
Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development
- Alexey Ruzov, Y. Tsenkina, +12 authors P. D. De Sousa
- Biology, Medicine
- Cell Research
- 12 July 2011
Methylation of cytosine is a DNA modification associated with gene repression. Recently, a novel cytosine modification, 5-hydroxymethylcytosine (5-hmC) has been discovered. Here we examine 5-hmC… Expand
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