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Role of gob-5 in mucus overproduction and airway hyperresponsiveness in asthma
- A. Nakanishi, S. Morita, +6 authors M. Fujino
- Medicine, Biology
- Proceedings of the National Academy of Sciences…
- 10 April 2001
Airway hyperresponsiveness (AHR), goblet cell metaplasia, and mucus overproduction are important features of bronchial asthma. To elucidate the molecular mechanisms behind these pulmonary… Expand
Increased expression of the human Ca2+-activated Cl- channel 1 (CaCC1) gene in the asthmatic airway.
- M. Hoshino, S. Morita, +7 authors M. Fujino
- Biology, Medicine
- American journal of respiratory and critical care…
- 15 April 2002
Mucus overproduction is a clinical feature of asthma. Ca2+-activated Cl- channel 1 (CaCC1) has been identified as a protein that is expressed in intestinal epithelia and that plays an important role… Expand
Modification of LC Phenotype and Suppression of Contact Hypersensitivity Response by Stress
- J. Hosoi, T. Tsuchiya, +4 authors J. Koyama
- Journal of cutaneous medicine and surgery
- 1 October 1998
Background: Stress is thought to exacerbate a number of diseases, some of which are skin disorders. Epidermal Langerhans' cells play a major role in cutaneous immune reactions. Objective: The effects… Expand
Putrescine-dependent invasive capacity of rat ascites hepatoma cells.
The effects of inhibitors of polyamine synthesis on the invasive capacity of rat ascites hepatoma (LC-AH) cells were examined by in vitro assay of penetration of the LC-AH cells through a monolayer… Expand
Cyclooxygenase-2/prostaglandin E2 accelerates the healing of gastric ulcers via EP4 receptors.
- R. Hatazawa, A. Tanaka, +4 authors K. Takeuchi
- American journal of physiology. Gastrointestinal…
- 1 October 2007
We examined the involvement of cyclooxygenase (COX)-1 as well as COX-2 in the healing of gastric ulcers and investigated which prostaglandin (PG) EP receptor subtype is responsible for the… Expand
2.W15.2 Mechanism of the production of small dense LDL (sLDL) in hypertriglyceridemia
Effects of Sialagogues on Ornithine Decarboxylase Induction and Proto-oncogene Expression in Murine Parotid Gland
- M. Kawano, A. Ueno, Y. Ashida, N. Matsumoto, H. Inoue
- Chemistry, Medicine
- Journal of dental research
- 1 December 1992
The mechanism of a sialagogue-induced increase in ornithine decarboxylase (ODC) activity and the expressions of proto-oncogenes in murine parotid gland were investigated by use of isoproterenol… Expand
Induction of ornithine decarboxylase by sialagogues in a human parotid gland adenocarcinoma cell line.
- A. Ueno, M. Kawano, Y. Ashida, F. Kinoshita, H. Inoue
- Chemistry, Medicine
- Biochemistry international
- 1 May 1991
Ornithine decarboxylase in a human parotid gland adenocarcinoma cell line was induced by both cholinergic (carbachol) and beta-adrenergic (isoproterenol) sialagogues. The enzyme protein level,… Expand