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The genome of the model beetle and pest Tribolium castaneum
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agriculturalExpand
Laccase 2 is the phenoloxidase gene required for beetle cuticle tanning.
TLDR
The hypothesis that two isoforms of laccase 2 generated by alternative splicing catalyze larval, pupal, and adult cuticle tanning in Tribolium is supported. Expand
Functional specialization among insect chitinase family genes revealed by RNA interference
TLDR
Functional specialization among insect chitinase family genes, primarily during the molting process, is indicated and a biological rationale for the presence of a large assortment of chit inase-like proteins is provided. Expand
The Tribolium chitin synthase genes TcCHS1 and TcCHS2 are specialized for synthesis of epidermal cuticle and midgut peritrophic matrix
Functional analysis of the two chitin synthase genes, TcCHS1 and TcCHS2, in the red flour beetle, Tribolium castaneum, revealed unique and complementary roles for each gene. TcCHS1‐specific RNAExpand
Domain organization and phylogenetic analysis of the chitinase-like family of proteins in three species of insects.
A bioinformatics-based investigation of three insect species with completed genome sequences has revealed that insect chitinase-like proteins (glycosylhydrolase family 18) are encoded by a ratherExpand
Insect chitinase and chitinase-like proteins
TLDR
Results of RNA interference experiments demonstrate that at least some of these chitinases belonging to different groups serve non-redundant functions and are essential for insect survival, molting or development. Expand
Genomics, transcriptomics, and peptidomics of neuropeptides and protein hormones in the red flour beetle Tribolium castaneum.
TLDR
The authors' analysis of Tribolium indicates that, during insect evolution, genes for neuropeptides and protein hormones are often duplicated or lost. Expand
Characterization of two chitin synthase genes of the red flour beetle, Tribolium castaneum, and alternate exon usage in one of the genes during development.
TLDR
It is proposed that the two isoforms of the TcCHS1 enzyme are used predominantly for the formation of chitin in embryonic and pupal cuticles, whereas Tc CHS2 is utilized primarily for the synthesis of peritrophic membrane-associated chit in the midgut. Expand
Molecular and Functional Analyses of Amino Acid Decarboxylases Involved in Cuticle Tanning in Tribolium castaneum*
TLDR
Dynamic mechanical analysis of elytral cuticle from beetles with depleted TcADC transcripts revealed diminished cross-linking of cuticular components, further confirming the important role of oxidation products of NBAD as cross- linking agents during cuticle tanning. Expand
Chitin synthases are required for survival, fecundity and egg hatch in the red flour beetle, Tribolium castaneum.
TLDR
It is demonstrated that the two chitin synthase genes have additional roles in embryonic and adult development in the red flour beetle and Tribolium castaneum and that these genes are required for all types of molt. Expand
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